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Expert Opinion on Drug Metabolism & Toxicology, 2019
Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the management of invasive fungal infections (IFIs), particularly for select antifungal agents with a well-defined exposure–response relationship and an unpredictable ...
Jamie John+3 more
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Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the management of invasive fungal infections (IFIs), particularly for select antifungal agents with a well-defined exposure–response relationship and an unpredictable ...
Jamie John+3 more
semanticscholar +1 more source
Therapeutic drug monitoring with biologic agents in immune mediated inflammatory diseases
Expert Review of Clinical Immunology, 2019Introduction: Biologic therapy has revolutionized the treatment of immune mediated inflammatory diseases (IMID), such as inflammatory bowel disease (IBD), rheumatoid and psoriatic arthritis, ankylosing spondylitis and psoriasis.
K. Papamichael+4 more
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Principles of therapeutic drug monitoring
Postgraduate Medicine, 1981Biochemical monitoring is generally advised for drugs that are potentially toxic, have a narrow therapeutic range, or are prescribed for life-threatening disease. Monitoring should not be attempted until the serum concentration reaches a plateau, or steady state, and sampling must be timed carefully.
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Wearable glove-embedded sensors for therapeutic drug monitoring in sweat for personalized medicine
Chemical Engineering Journal, 2022Paulo A. Raymundo‐Pereira+3 more
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Introduction to therapeutic drug monitoring
2007Therapeutic drug monitoring is useful for individual dosage adjustment and avoiding drug toxicity for certain drugs with a narrow therapeutic window. However, only relatively few drugs require therapeutic drug monitoring and most of these drugs are used for treating a chronic condition.
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Antimicrobial Therapeutic Drug Monitoring
Clinics in Laboratory Medicine, 1981Antimicrobial agents can be allergenic, have toxic effects on the function of certain organ systems, produce idiosyncratic reactions, alter the normal bacterial flora of the body, and adversely interact with other medications. All possible untoward side effects must be carefully monitored when prescribing antimicrobial agents.
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Therapeutic drug monitoring for immunosuppressants
Clinica Chimica Acta, 2001Immunosuppressants have significantly increased patient survival, e.g. in renal transplant up to 90% for the first year.Four immunosuppressants are used for clinical applications in the United States: cyclosporine (CsA) (Sandimmune and Neoral), FK 506-tacrolimus (ProGraf), mycophenolic mofetil (CellCept)--the prodrug for the mycophenolic acid (MPA ...
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Therapeutic Monitoring of Antiarrhythmic Drugs
Therapeutic Drug Monitoring, 1980Antiarrhythmic drugs are potent agents which generally have narrow therapeutic indices. The consequences of administering either too little or too much can be life-threatening. Consequently, monitoring of plasma concentrations of these agents is an important part of rational antiarrhythmic therapy.
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Therapeutic Drug Monitoring in Pregnancy
Therapeutic Drug Monitoring, 2012Therapeutic drug monitoring (TDM) is commonly recommended to optimize drug dosing regimens of various medications. It has been proposed to guide therapy in pregnant women, in whom physiological changes may lead to altered pharmacokinetics resulting in difficulty in predicting the appropriate drug dosage.
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