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Therapeutic drug monitoring of systemic antifungal agents: a pragmatic approach for adult and pediatric patients

Expert Opinion on Drug Metabolism & Toxicology, 2019
Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the management of invasive fungal infections (IFIs), particularly for select antifungal agents with a well-defined exposure–response relationship and an unpredictable ...
Jamie John   +3 more
semanticscholar   +1 more source

Therapeutic drug monitoring with biologic agents in immune mediated inflammatory diseases

Expert Review of Clinical Immunology, 2019
Introduction: Biologic therapy has revolutionized the treatment of immune mediated inflammatory diseases (IMID), such as inflammatory bowel disease (IBD), rheumatoid and psoriatic arthritis, ankylosing spondylitis and psoriasis.
K. Papamichael   +4 more
semanticscholar   +1 more source

Principles of therapeutic drug monitoring

Postgraduate Medicine, 1981
Biochemical monitoring is generally advised for drugs that are potentially toxic, have a narrow therapeutic range, or are prescribed for life-threatening disease. Monitoring should not be attempted until the serum concentration reaches a plateau, or steady state, and sampling must be timed carefully.
openaire   +2 more sources

Therapeutic drug monitoring

Clinical Pharmacology and Therapeutics, 1988
R, Spector   +3 more
openaire   +4 more sources

Wearable glove-embedded sensors for therapeutic drug monitoring in sweat for personalized medicine

Chemical Engineering Journal, 2022
Paulo A. Raymundo‐Pereira   +3 more
semanticscholar   +1 more source

Introduction to therapeutic drug monitoring

2007
Therapeutic drug monitoring is useful for individual dosage adjustment and avoiding drug toxicity for certain drugs with a narrow therapeutic window. However, only relatively few drugs require therapeutic drug monitoring and most of these drugs are used for treating a chronic condition.
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Antimicrobial Therapeutic Drug Monitoring

Clinics in Laboratory Medicine, 1981
Antimicrobial agents can be allergenic, have toxic effects on the function of certain organ systems, produce idiosyncratic reactions, alter the normal bacterial flora of the body, and adversely interact with other medications. All possible untoward side effects must be carefully monitored when prescribing antimicrobial agents.
openaire   +3 more sources

Therapeutic drug monitoring for immunosuppressants

Clinica Chimica Acta, 2001
Immunosuppressants have significantly increased patient survival, e.g. in renal transplant up to 90% for the first year.Four immunosuppressants are used for clinical applications in the United States: cyclosporine (CsA) (Sandimmune and Neoral), FK 506-tacrolimus (ProGraf), mycophenolic mofetil (CellCept)--the prodrug for the mycophenolic acid (MPA ...
openaire   +3 more sources

Therapeutic Monitoring of Antiarrhythmic Drugs

Therapeutic Drug Monitoring, 1980
Antiarrhythmic drugs are potent agents which generally have narrow therapeutic indices. The consequences of administering either too little or too much can be life-threatening. Consequently, monitoring of plasma concentrations of these agents is an important part of rational antiarrhythmic therapy.
openaire   +3 more sources

Therapeutic Drug Monitoring in Pregnancy

Therapeutic Drug Monitoring, 2012
Therapeutic drug monitoring (TDM) is commonly recommended to optimize drug dosing regimens of various medications. It has been proposed to guide therapy in pregnant women, in whom physiological changes may lead to altered pharmacokinetics resulting in difficulty in predicting the appropriate drug dosage.
openaire   +2 more sources

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