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Therapeutic drug monitoring of cyclosporine
Transplantation Proceedings, 2004Therapeutic drug monitoring of cyclosporine has been established as part of the routine clinical treatment for patients after organ transplantation. The inability to define optimal dose (maximize efficacy/minimize toxicity) has been a problem related to drug monitoring of cyclosporine.
A, Jorga, D W, Holt, A, Johnston
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Immunoassays in Therapeutic Drug Monitoring
Clinics in Laboratory Medicine, 1987Numerous immunoassay methods are now in routine use for therapeutic drug monitoring of drugs and metabolites. Most methods are homogeneous immunoassays with excellent specificity, accuracy, and precision. In addition, these assays are readily automated, and commercial versions of theses reagents are available with dedicated instrumentation. This report
L J, Blecka, G J, Jackson
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Therapeutic Drug Monitoring of the Antimycobacterial Drugs
Clinics in Laboratory Medicine, 1996Because MDR tuberculosis and MAC are difficult to treat, TDM with the antimycobacterial drugs has become the standard of practice at NJC. By combining specific and sensitive assays, carefully collected samples, and clinical expertise, we are able to control and optimize antimycobacterial drug therapy.
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[Therapeutic drug monitoring of antimicrobials].
Nederlands tijdschrift voor geneeskunde, 2014Contains fulltext : 136169.pdf (Publisher’s version ) (Closed access)
Mouton, J.W., Aarnoutse, R.E.
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Therapeutic Drug Monitoring of Lamotrigine
Annals of Pharmacotherapy, 2002OBJECTIVE: To evaluate the usefulness of routine monitoring of serum lamotrigine concentration. DATA SOURCE: Literature was accessed through MEDLINE (1990–January 2001).
Elaine, Chong, L Lee, Dupuis
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Therapeutic Drug Monitoring in Saliva
Clinical Pharmacokinetics, 1978The observation that drug concentrations in saliva are often proportional to the concentrations in plasma has led to the suggestion that in therapeutic drug monitoring, or in pharmacokinetic studies in general, saliva might be substituted for plasma.
M, Danhof, D D, Breimer
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Office Therapeutic Drug Monitoring
Primary Care: Clinics in Office Practice, 1986Considerations necessary for appropriate therapeutic drug monitoring in the office practice setting have been presented. Practical issues focusing on clinical pharmacokinetics as well as serum drug concentration evaluation methods and techniques have been reviewed, with emphasis on orally administered medications.
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Principles of therapeutic drug monitoring
Postgraduate Medicine, 1981Biochemical monitoring is generally advised for drugs that are potentially toxic, have a narrow therapeutic range, or are prescribed for life-threatening disease. Monitoring should not be attempted until the serum concentration reaches a plateau, or steady state, and sampling must be timed carefully.
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Antiepileptic Therapeutic Drug Monitoring
Clinics in Laboratory Medicine, 1981The effort to employ therapeutic drug monitoring in the management of patients with convulsive disorders has been extremely successful. Fortunately, the drugs used by the majority of these patients are readily measured in plasma, and in most cases the plasma concentration is a valid measure of the appropriateness of the dosage of drug administered ...
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