Results 11 to 20 of about 51,423 (237)
Evidence of comparative efficacy should have a formal role in European drug approvals [PDF]
, 2011 Despite methodological concerns, comparative efficacy evidence should be required at the time of drug approval, says Corinna Sorenson and colleagues, to allow patients, clinicians, and other healthcare decision makers to determine whether a new drug is ...
Cylus, Jonathan +3 more
core +1 more source
WHAT IS THERAPEUTIC EQUIVALENCE OF GENERIC DRUG AND HOW TO PROVE IT
Рациональная фармакотерапия в кардиологии, 2016 The problem of generic drugs use in clinical practice and confirmation of their therapeutic equivalence is discussed. The significance of studies on generic drugs bioequivalence, as well as details of international practice and regulations in this area ...
N. P. Kutishenko +2 more
doaj +1 more source
PROBLEM OF GENERIC REPLACEMENT: ADVANTAGES AND DISADVANTAGES
Рациональная фармакотерапия в кардиологии, 2016 The main differences between original and generic drugs as well as registration criteria for generics are described. Possible reasons of discrepancy in bioequivalence and therapeutic equivalence of original and generic drugs are reviewed. The examples of
S. N. Tolpygina, S. Yu. Martsevich
doaj +3 more sources
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study the therapeutic equivalence of original and generic fosinopril in patients with arterial hypertension (HT) of 1-2 degrees, and to evaluate the cost effectiveness of original drug substitution with generic. Material and methods.
N. P. Kutishenko +3 more
doaj +1 more source
Efficacy and Patient-Reported Outcomes of a New Mometasone Cream Treating Atopic Eczema [PDF]
, 2012 This double-blind controlled phase II study was conducted to compare a newly developed formulation of mometasone furoate with a water content of 33% (Monovo (R) Cream) and with a smooth consistency versus the commercially available fatty cream of ...
Ruzicka, Thomas +2 more
core +1 more source
Архивъ внутренней медицины, 2012 The relevance of cardiovascular disease in the world and in Russia causes including calls for patient compliance with medical recommendations. Compliance, in turn, depends on the cost of medicines. From an economic point of view generic drugs appear in a
В. П. Михин +1 more
doaj +1 more source
Регуляторные исследования и экспертиза лекарственных средств, 2019 This article looks into interchangeability and therapeutic equivalence of innovator and generic anticonvulsants — the first-generation and new antiepileptic drugs (AEDs).
V. V. Arkhipov +4 more
doaj +1 more source
Guidelines for the recording and evaluation of pharmaco-EEG data in man: the International Pharmaco-EEG Society (IPEG) [PDF]
, 2012 The International Pharmaco-EEG Society (IPEG) presents updated guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-EEG data in man.
BABILONI, CLAUDIO +24 more
core +1 more source
Кардиоваскулярная терапия и профилактика, 2015 Aim. To study therapeutic equivalence of rosuvastatin generic and original medication and to conduct the pharmacoeconomic analysis to compare the impact of the drug on direct expenses in secondary prevention for the patients with chronic ischemic heart ...
E. I. Tarlovskaya +3 more
doaj +1 more source
Безопасность и риск фармакотерапии, 2019 Presently, an active search for modern drugs for the treatment of multiple sclerosis is ongoing. Since the treatment with original drugs is expensive, therefore, the development of local biosimilars is underway, which at a lower cost should be ...
D. O. Gudz +4 more
doaj +1 more source