Results 21 to 30 of about 28,368 (156)

QUALITATIVE DRUG: WHAT SHOULD IT LOOK LIKE?

open access: yesРациональная фармакотерапия в кардиологии, 2016
Drug quality in modern market is discussed. There is an increase of a number of drugs that don’t meet to the quality requirements.Most of them are produced by Russian manufacturers, which number has also increased recently.
V. V. Iakusevich
doaj   +1 more source

Clinical and Pharmacological Approaches to the Prescription of Centrally Acting Antihypertensive Drugs for Uncontrolled Arterial Hypertension

open access: yesРациональная фармакотерапия в кардиологии, 2020
Episodes of rapid increase in blood pressure due to uncontrolled arterial hypertension, previously known as a hypertensive urgency, is common clinical condition which many of practicing physicians are encountered daily.
A. V. Strygin   +3 more
doaj   +1 more source

Comparación de la equivalencia terapéutica de dos productos de bisoprolol – hidroclorotiazida en pacientes con hipertensión arterial

open access: yesRevista Colombiana de Cardiología, 2020
Resumen: Objetivo: Evaluar la equivalencia terapéutica de dos marcas comerciales de bisoprolol -hidroclorotiazida como terapia antihipertensiva. Método: Estudio prospectivo, doble ciego, doble falso, aleatorizado, de grupos paralelos, en el que se ...
Ulises Leal, David Rincón
doaj   +1 more source

Estudos de medicamentos biosimilares Studies on biosimilar medications

open access: yesJornal Vascular Brasileiro, 2010
No Brasil, o registro de novos medicamentos é feito apenas quando a agência reguladora - Agência Nacional de Vigilância Sanitária (Anvisa) - se satisfaz plenamente com as evidências de sua qualidade, eficácia e segurança, apresentadas por uma indústria ...
Winston Bonetti Yoshida
doaj   +1 more source

Bioequivalence and therapeutic equivalence of psychotropic drugs

open access: yesPostępy Psychiatrii i Neurologii, 2015
Introduction to the market of generic drugs has increased access to modern therapies and enabled significant reduction of their cost, leading to containment of public expenditures on drug reimbursement. The assessment of bioequivalence of reference and generic drugs is based on the assumption that two different drug products are equivalent when their ...
K. Rokita, E. Balkowiec-Iskra, G. Cessak
openaire   +1 more source

The problem of choosing between the original and of generic drugs in patients with overweight and obesity

open access: yesОжирение и метаболизм, 2013
This review article discusses the similarities and differences in the research, production and use in clinical practice, original and generic drugs. Reproduced drugs (generics) present on the Russian pharmaceutical market that have the bioequivalence ...

doaj   +1 more source

Original drugs and generics: are there any differences from the clinician’s point of view?

open access: yesРациональная фармакотерапия в кардиологии
The article defines the original drug (OD) and examines the history of the appearance of generic drugs (GD), as well as the evolution of views to prove their bioequivalence to OD.
S. Yu. Martsevich   +2 more
doaj   +1 more source

Correlation of reference and generic fluconazole-based drugs

open access: yesМедицинский совет, 2020
The article describes the basic rules for the selection of a systemic antifungal drug from the fluconazole-based preparations available on the Russian pharmaceutical market.
A. S. Dukhanin
doaj   +1 more source

Interchangeable medicines: impact of expenses from the perspective of customers of a startup from Minas Gerais

open access: yesJornal de Assistência Farmacêutica e Farmacoeconomia
Objectives: The objective of this study was to conduct a cost-minimization evaluation of the potential interchangeability between prescribed medications from the patient’s pers-pective, using information from Far.me, a startup that offers individualized
Cícero Quintão Celestino   +4 more
doaj   +1 more source

Impact on Bacterial Resistance of Therapeutically Nonequivalent Generics: The Case of Piperacillin-Tazobactam.

open access: yesPLoS ONE, 2016
Previous studies have demonstrated that pharmaceutical equivalence and pharmacokinetic equivalence of generic antibiotics are necessary but not sufficient conditions to guarantee therapeutic equivalence (better called pharmacodynamic equivalence).
Carlos A Rodriguez   +4 more
doaj   +1 more source

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