Results 21 to 30 of about 2,032,347 (297)

PREDICTION OF THE INFLUENCE OF ORIGINAL AND GENERIC ROSUVASTATIN ON DIRECT MEDICAL COSTS OF SECONDARY PREVENTION IN PATIENTS WITH CHRONIC TYPES OF ISCHEMIC HEART DISEASE

Кардиоваскулярная терапия и профилактика, 2015
Aim. To study therapeutic equivalence of rosuvastatin generic and original medication and to conduct the pharmacoeconomic analysis to compare the impact of the drug on direct expenses in secondary prevention for the patients with chronic ischemic heart ...
E. I. Tarlovskaya, G. I. Nechaeva, S. V. Malchikova, А. А. Semenkin   +3 more
doaj   +1 more source

Safety of Use of Russian Biosimilars of Interferon Beta-1b in the Treatment of Multiple Sclerosis: a Meta-analysis of Original Studies

Безопасность и риск фармакотерапии, 2019
Presently, an active search for  modern drugs for  the  treatment of multiple sclerosis is ongoing. Since  the  treatment with original drugs is expensive, therefore, the  development of local biosimilars is underway, which at a lower  cost should be ...
D. O. Gudz, A. E. Krasnov, R. N. Mamleev, R. K. Kagirov, M. L. Maximov   +4 more
doaj   +1 more source

A COMPARATIVE STUDY OF THE EFFICACY AND TOLERABILITY OF ORIGINAL AND GENERIC BISOPROLOL IN MONOTHERAPY OR IN COMBINATION WITH S-AMLODIPINE AND INDAPAMIDE IN PATIENTS WITH ARTERIAL HYPERTENSION 1-2 DEGREES. RESULTS OF THE CLINICAL RANDOMIZED CROSSOVER STUDY

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study the clinical equivalence of original and generic drugs of bisoprolol in patients with arterial hypertension (HT) 1-2 degrees according to protocol recommended by the Society of Cardiology of the Russian Federation for comparative studies ...
S. Yu. Martsevich, S. N. Tolpygina, V. P. Voronina, O. V. Lerman, Yu. V. Lukina, N. A. Dmitrieva, I. V. Vashurina   +6 more
doaj   +1 more source

Clinical and Pharmacological Approaches to the Prescription of Centrally Acting Antihypertensive Drugs for Uncontrolled Arterial Hypertension

Рациональная фармакотерапия в кардиологии, 2020
Episodes of rapid increase in blood pressure due to uncontrolled arterial hypertension, previously known as a hypertensive urgency, is common clinical condition which many of practicing physicians are encountered daily.
A. V. Strygin, B. E. Tolkachev, A. O. Strygina, A. M. Dotsenko   +3 more
doaj   +1 more source

Bioequivalence of a Hydroxyurea Oral Suspension (100 mg/mL) and Xromi® 100 mg/mL Oral Solution (100 mg Hydroxycarbamide) under Fasting Conditions: A Randomised, Open-label, Single-dose, Two-period Crossover Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Hydroxyurea oral suspension is approved as an adjunctive treatment for Sickle Cell Disease (SCD) and Myeloproliferative Disorders (MPD).
Sunil Jaiswal, Arun Chaudhary, Mamta Sharma, Mansingh Rajput, Badrinath Sangle, Kamlesh Londhe   +5 more
doaj   +1 more source

Trace Equivalence Decision: Negative Tests and Non-determinism [PDF]

, 2011
We consider security properties of cryptographic protocols that can be modeled using the notion of trace equivalence. The notion of equivalence is crucial when specifying privacy-type properties, like anonymity, vote-privacy, and unlinkability.
Hubert Comon-Lundh, Stéphanie Delaune, Cheval, Vincent, Delaune, Stéphanie, Vincent Cheval, Comon-Lundh, Hubert   +5 more
core   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Comparación de la equivalencia terapéutica de dos productos de bisoprolol – hidroclorotiazida en pacientes con hipertensión arterial

Revista Colombiana de Cardiología, 2020
Resumen: Objetivo: Evaluar la equivalencia terapéutica de dos marcas comerciales de bisoprolol -hidroclorotiazida como terapia antihipertensiva. Método: Estudio prospectivo, doble ciego, doble falso, aleatorizado, de grupos paralelos, en el que se ...
Ulises Leal, David Rincón
doaj   +1 more source

Bioequivalence and therapeutic equivalence of psychotropic drugs

Postępy Psychiatrii i Neurologii, 2015
Introduction to the market of generic drugs has increased access to modern therapies and enabled significant reduction of their cost, leading to containment of public expenditures on drug reimbursement. The assessment of bioequivalence of reference and generic drugs is based on the assumption that two different drug products are equivalent when their ...
K. Rokita, E. Balkowiec-Iskra, G. Cessak
openaire   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source