Results 11 to 20 of about 2,032,347 (297)

WHAT IS THERAPEUTIC EQUIVALENCE OF GENERIC DRUG AND HOW TO PROVE IT [PDF]

open access: yesРациональная фармакотерапия в кардиологии, 2016
The problem of generic drugs use in clinical practice and confirmation of their therapeutic equivalence is discussed. The significance of studies on generic drugs bioequivalence, as well as details of international practice and regulations in this area ...
N. P. Kutishenko   +2 more
doaj   +2 more sources

Unravelling the “equivalence paradox”: An exploration of possible mechanistic explanations for the equivalence of the person-centred approach and cognitive behavioural therapy [PDF]

open access: yes, 2011
This project adopted a neuroscience perspective to explore the reason for the Equivalence Paradox, that is the finding that quite different therapeutic modalities are, as an approximation, equally effective.
Garman, Andrew J.
core   +2 more sources

VALUE OF THERAPEUTIC EQUIVALENCE IN SUBSTITUTION OF ORIGINAL DRUG WITH GENERIC BY EXAMPLE OF FOSINIPRIL

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study the therapeutic equivalence of original and generic fosinopril in patients with arterial hypertension (HT) of 1-2 degrees, and to evaluate the cost effectiveness of original drug substitution with generic. Material and methods.
N. P. Kutishenko   +3 more
doaj   +1 more source

ECONOMIC REASONS FOR GENERIC CHOICE

open access: yesРациональная фармакотерапия в кардиологии, 2016
Many generic medicines appear in the pharmaceutical market now. However, they are not always completely comparable with original drugs on efficacy and safety. In this article pharmacoeconomical estimation of some generics and original drugs was performed
N. P. Kutishenko   +3 more
doaj   +1 more source

ДЖЕНЕРИЧЕСКИЕ СТАТИНЫ В КЛИНИЧЕСКОЙ ПРАКТИКЕ: ДЕШЕВЫЕ ЗАМЕНИТЕЛИ ИЛИ ДОСТОЙНАЯ АЛЬТЕРНАТИВА БРЕНДАМ. АТОРВАСТАТИН

open access: yesАрхивъ внутренней медицины, 2012
The relevance of cardiovascular disease in the world and in Russia causes including calls for patient compliance with medical recommendations. Compliance, in turn, depends on the cost of medicines. From an economic point of view generic drugs appear in a
В. П. Михин   +1 more
doaj   +1 more source

Deciding equivalence-based properties using constraint solving [PDF]

open access: yes, 2013
Formal methods have proved their usefulness for analyzing the security of protocols. Most existing results focus on trace properties like secrecy or authentication.
Véronique Cortier   +5 more
core   +1 more source

QUALITATIVE DRUG: WHAT SHOULD IT LOOK LIKE?

open access: yesРациональная фармакотерапия в кардиологии, 2016
Drug quality in modern market is discussed. There is an increase of a number of drugs that don’t meet to the quality requirements.Most of them are produced by Russian manufacturers, which number has also increased recently.
V. V. Iakusevich
doaj   +1 more source

Current Approaches to Demonstration of Therapeutic Equivalence of Locally-Acting Gastrointestinal Drugs

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2021
Evolution of knowledge about pharmacokinetics and pharmacodynamics of locally acting products, and an increase in the number of generics and medicines under development have laid the ground for the development of new scientific approaches to planning and
E. V. Gorbunova   +3 more
doaj   +1 more source

Efficacy and safety of a switch from twice-daily tacrolimus to once-daily generic tacrolimus in stable liver transplant patients

open access: yesKorean Journal of Transplantation, 2021
Background : Once-daily tacrolimus reduces non-compliance relative to twice-daily tacrolimus. However, little is known about the safety and efficacy of conversion from twice-daily tacrolimus to generic once-daily tacrolimus in liver transplantation (LT).
Jong Man Kim   +17 more
doaj   +1 more source

New Anticonvulsants: Interchangeability Issues and the Use of Generic Anticonvulsants in Clinical Practice

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2019
This article looks into interchangeability and therapeutic equivalence of innovator and generic anticonvulsants — the first-generation and new antiepileptic drugs (AEDs).
V. V. Arkhipov   +4 more
doaj   +1 more source

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