Results 21 to 30 of about 3,107,552 (340)
Evidence of comparative efficacy should have a formal role in European drug approvals [PDF]
, 2011 Despite methodological concerns, comparative efficacy evidence should be required at the time of drug approval, says Corinna Sorenson and colleagues, to allow patients, clinicians, and other healthcare decision makers to determine whether a new drug is ...
Cylus, Jonathan +3 more
core +2 more sources
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study the therapeutic equivalence of original and generic fosinopril in patients with arterial hypertension (HT) of 1-2 degrees, and to evaluate the cost effectiveness of original drug substitution with generic. Material and methods.
N. P. Kutishenko +3 more
doaj +1 more source
ECONOMIC REASONS FOR GENERIC CHOICE
Рациональная фармакотерапия в кардиологии, 2016 Many generic medicines appear in the pharmaceutical market now. However, they are not always completely comparable with original drugs on efficacy and safety. In this article pharmacoeconomical estimation of some generics and original drugs was performed
N. P. Kutishenko +3 more
doaj +1 more source
PROBLEM OF GENERIC REPLACEMENT: ADVANTAGES AND DISADVANTAGES
Рациональная фармакотерапия в кардиологии, 2016 The main differences between original and generic drugs as well as registration criteria for generics are described. Possible reasons of discrepancy in bioequivalence and therapeutic equivalence of original and generic drugs are reviewed. The examples of
S. N. Tolpygina, S. Yu. Martsevich
doaj +3 more sources
Архивъ внутренней медицины, 2012 The relevance of cardiovascular disease in the world and in Russia causes including calls for patient compliance with medical recommendations. Compliance, in turn, depends on the cost of medicines. From an economic point of view generic drugs appear in a
В. П. Михин +1 more
doaj +1 more source
Efficacy and Patient-Reported Outcomes of a New Mometasone Cream Treating Atopic Eczema [PDF]
, 2012 This double-blind controlled phase II study was conducted to compare a newly developed formulation of mometasone furoate with a water content of 33% (Monovo (R) Cream) and with a smooth consistency versus the commercially available fatty cream of ...
Ruzicka, Thomas +2 more
core +1 more source
Регуляторные исследования и экспертиза лекарственных средств, 2019 This article looks into interchangeability and therapeutic equivalence of innovator and generic anticonvulsants — the first-generation and new antiepileptic drugs (AEDs).
V. V. Arkhipov +4 more
doaj +1 more source
Кардиоваскулярная терапия и профилактика, 2015 Aim. To study therapeutic equivalence of rosuvastatin generic and original medication and to conduct the pharmacoeconomic analysis to compare the impact of the drug on direct expenses in secondary prevention for the patients with chronic ischemic heart ...
E. I. Tarlovskaya +3 more
doaj +1 more source
Revista Colombiana de Cardiología, 2020 Resumen: Objetivo: Evaluar la equivalencia terapéutica de dos marcas comerciales de bisoprolol -hidroclorotiazida como terapia antihipertensiva. Método: Estudio prospectivo, doble ciego, doble falso, aleatorizado, de grupos paralelos, en el que se ...
Ulises Leal, David Rincón
doaj +1 more source
Revista Peruana de Medicina Experimental y Salud Pública, 2019 The objective of the study was to determine the therapeutic equivalence evaluated through in vitro studies of four brands of drugs containing amoxicillin, doxycycline, and fluconazole purchased at pharmaceutical facilities in Metropolitan Lima, and to ...
M. Grande-Ortíz +4 more
semanticscholar +1 more source