Results 1 to 10 of about 4,922 (132)

Is bad breath associated with dyspepsia? An association and an equivalence study [PDF]

Brazilian Oral Research, 2023
Halitosis affects all populations worldwide. The presence of chronic halitosis may be related to a health problem. Patients with bad breath usually seek a gastroenterologist and, in some cases, invasive and expensive exams, such as digestive endoscopy ...
Nádia Cristina Pinheiro RODRIGUES, Alexandre ABRÃO NETO, Paulo NADANOVSKY   +2 more
doaj   +1 more source

Bioequivalence study between two formulations of 10mg lenalidomide capsules in healthy male subjects under fasting conditions

Brazilian Journal of Oncology, 2023
OBJECTIVE: To evaluate pharmaceutical bioequivalence between two formulations of 10mg lenalidomide capsules in healthy male subjects under fasting conditions.
Carlos Sverdloff, Vinicius Marcondes Rezende, Ligia de Cassia Val, Nelly Cristina Castro, Maria Elena Cedano Limón, Mohammad H. Badii, Sreekanth Kakarla, Murali Pendela, Lygia Bonnato   +8 more
doaj   +1 more source

Bioequivalence/bioavailability study of a new formulation of imatinib mesylate 100 mg coated tablets versus Glivec® in Brazilian healthy male volunteers in fed state

Revista Brasileira de Cancerologia, 2023
Introduction: Imatinib mesylate is currently the first-line oral treatment for all stages of chronic myeloid leukemia (CML) and is also used in some cases of gastrointestinal stromal tumor (GIST) and acute lymphoblastic leukemia (ALL).
Carlos Eduardo Sverdloff, Vinicius Marcondes Rezende, Paulo Alexandre Rebelo Galvinas, Guilherme Araújo Pinto, Lygia Nerath Bonanato, Fernando Bastos Canton Pacheco   +5 more
doaj   +1 more source

Bioequivalence assessment of the two brands of glimepiride tablets [PDF]

Vojnosanitetski Pregled, 2006
Background/Aim. Glimepiride, as an antidiabetic from the group of sulfonylurea, is administered perorally in the treatment of diabetes mellitus. The aim of this study was to compare pharmacokinetic profiles and relative bioavailabilities of the two oral ...
Jovanović Dušan, Stojšić Dragan, Zlatković Milica, Jović-Stošić Jasmina, Jovanović Miodrag   +4 more
doaj   +1 more source

DISCONTINUATION RATES FOLLOWING A SWITCH FROM A REFERENCE TO A BIOSIMILAR BIOLOGIC IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS [PDF]

Arquivos de Gastroenterologia, 2020
BACKGROUND: Biologics have revolutionized the treatment of inflammatory bowel disease (IBD). However, these drugs had a significant influence on treatment-related costs, which resulted in the development of biosimilars.
Natália Sousa Freitas QUEIROZ, Rogerio SAAD-HOSSNE, Renata de Sá Brito FRÓES, Francisco Guilherme Cancela e PENNA, Stefania Burjack GABRIEL, Adalberta Lima MARTINS, Fabio Vieira TEIXEIRA   +6 more
doaj   +1 more source

Fundamental movement skill proficiency and objectively measured physical activity in children with bronchiectasis: a cross-sectional study

BMC Pulmonary Medicine, 2021
Background Bronchiectasis is a major contributor to respiratory morbidity and healthcare utilization in children. Children with bronchiectasis exhibit low levels of physical activity (PA) and poor fundamental movement skills (FMS) may be a contributing ...
Barbara Joschtel, Sjaan R. Gomersall, Sean Tweedy, Helen Petsky, Anne B. Chang, Stewart G. Trost   +5 more
doaj   +1 more source

Study of dissolution profiles of Аmlodipine tablets with enalapril

Ukrainian Scientific Medical Youth Journal, 2022
quality assurance in the production of medicines is a comprehensive concept. The quality of medicines must be guaranteed at all stages of production - from development, research and production to implementation and optimal use.
Nataliia Behei, Oksana Tryhubchak
doaj   +1 more source

Soft skin-interfaced mechano-acoustic sensors for real-time monitoring and patient feedback on respiratory and swallowing biomechanics

npj Digital Medicine, 2022
Swallowing is a complex neuromuscular activity regulated by the autonomic nervous system. Millions of adults suffer from dysphagia (impaired or difficulty swallowing), including patients with neurological disorders, head and neck cancer, gastrointestinal
Youn J. Kang, Hany M. Arafa, Jae-Young Yoo, Cagla Kantarcigil, Jin-Tae Kim, Hyoyoung Jeong, Seonggwang Yoo, Seyong Oh, Joohee Kim, Changsheng Wu, Andreas Tzavelis, Yunyun Wu, Kyeongha Kwon, Joshua Winograd, Shuai Xu, Bonnie Martin-Harris, John A. Rogers   +16 more
doaj   +1 more source

Metanálise de estudos de bioequivalência: a intercambiabilidade de genéricos e similares que contêm Hidroclorotiazida é possível, mas não àqueles com Maleato de Enalapril Meta-analysis for bioequivalence studies: interchangeability of generic drugs and similar containing Hydrochlorothiazide is possible but not with Enalapril Maleate

Brazilian Journal of Nephrology, 2010
INTRODUÇÃO: O programa de genéricos no Brasil propiciou maior acesso da população a medicamentos. Para garantir a intercambiabilidade entre medicamentos referência e genérico ou similar, é necessário que eles sejam bioequivalentes.
Renato Almeida Lopes, Francisco de Assis Rocha Neves   +1 more
doaj   +1 more source

ECONOMIC REASONS FOR GENERIC CHOICE

Рациональная фармакотерапия в кардиологии, 2016
Many generic medicines appear in the pharmaceutical market now. However, they are not always completely comparable with original drugs on efficacy and safety. In this article pharmacoeconomical estimation of some generics and original drugs was performed
N. P. Kutishenko, S. Y. Martsevich, S. N. Tolpygina, J. V. Lukina   +3 more
doaj   +1 more source