Results 11 to 20 of about 4,942 (152)

Pharmaceutical equivalency of locally and regionally manufactured generic pharmaceutical products in UAE

Saudi Pharmaceutical Journal, 2022
Generic drugs or generic medicines are pharmaceutical products manufactured to be equivalent to the brand/innovator drug products. They represent the majority of worldwide prescribed medicines; therefore, their quality is critical to maximize patients ...
Lamia Al Ali, Jayalakshmi Jagal, Jobi Joseph, Iman Saad Ahmed, Mutasem Rawas-Qalaji   +4 more
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Determinação de captopril por HPLC acoplado a espectômetro de massa: aplicação em estudo de bioequivalência - doi: 10.5020/18061230.2012.p13

Revista Brasileira em Promoção da Saúde, 2012
Objetivo: Avaliar a bioequivalência de três diferentes formulações de captopril 25mg (Capoten® como formulação de referência e Captopril produzido pela FURP e Farmanguinhos como formulações testes) em 24 voluntários saudáveis de ambos os sexos.
Aline Kércia Alves Soares, Manoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Gilberto de Nucci, Maria Elisabete Amaral de Moraes   +4 more
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Evaluation of Dilution Susceptibility Testing Methods for Aztreonam in Combination with Avibactam against Enterobacterales

Microbiology Spectrum, 2022
As multidrug and pan-resistance among Enterobacterales continue to increase, there is an urgent need for more therapeutic options to treat these infections.
C. J. Kelley, A. Kennedy-Mendez, O. N. Walser, M. T. Thwaites, F. F. Arhin, C. M. Pillar, D. A. Hufnagel   +6 more
doaj   +1 more source

Full-length recombinant antibodies from Escherichia coli: production, characterization, effector function (Fc) engineering, and clinical evaluation

mAbs, 2022
Although several antibody fragments and antibody fragment-fusion proteins produced in Escherichia coli (E. coli) are approved as therapeutics for various human diseases, a full-length monoclonal or a bispecific antibody produced in E.
Md Harunur Rashid
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Bioequivalence study of four different trademarks of enalapril maleate in spontaneously hypertensive rats Estudo da bioequivalência de quatro diferentes marcas comerciais de maleato de enalapril em ratos espontaneamente hipertensos

Acta Cirúrgica Brasileira, 2008
INTRODUCTION: High blood pressure is a systemic disease which has major clinical and psycho-social repercussions, involves a high morbidity-mortality rate and generates high costs for the health system.
Nilo César do Vale Baracho, Guilherme D'Andréa Saba Arruda, Lidinei José Alves, Márcio Felipe Salomon Carneiro, Matheus Teodoro Grilo Siqueira, Héctor Gustavo Arango, José Marcos dos Reis   +6 more
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The introduction of biosimilars of low molecular weight heparins in Europe: a critical review and reappraisal endorsed by the Italian Society for Haemostasis and Thrombosis (SISET) and the Italian Society for Angiology and Vascular Medicine (SIAPAV)

Thrombosis Journal, 2017
Recently, the European Medicines Agency (EMA) authorized the introduction and marketing of Thorinane® and Inhixa®, biosimilars of the Low Molecular Weight Heparin (LMWH) enoxaparin.
Davide Imberti, Marco Marietta, Hernan Polo Friz, Claudio Cimminiello   +3 more
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Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro

Molecular Therapy: Nucleic Acids, 2017
Tumor cells express a number of immunosuppressive molecules that can suppress anti-tumor immune responses. Efficient delivery of small interfering RNAs to treat a wide range of diseases including cancers remains a challenge.
Amy H. Lin, Christopher G. Twitty, Ryan Burnett, Andrew Hofacre, Leah A. Mitchell, Fernando Lopez Espinoza, Harry E. Gruber, Douglas J. Jolly   +7 more
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Determination of captopril by hplctandem mass spectrometry: application in a bioequivalence study [PDF]

Revista Brasileira em Promoção da Saúde, 2012
Objective: To assess three different captopril tablet formulations of 25mg for their bioavailability (Capoten® as the reference formulation and Captopril from FURP and Farmanguinhos as the test formulations) in 24 healthy volunteers of both sexes ...
Aline Kércia Alves Soares, Manoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Gilberto de Nucci, Maria Elisabete Amaral de Moraes   +4 more
doaj  

Intracerebral delivery of Carboplatin in combination with either 6 MV Photons or monoenergetic synchrotron X-rays are equally efficacious for treatment of the F98 rat glioma

Journal of Experimental & Clinical Cancer Research, 2012
Background The purpose of the present study was to compare side-by-side the therapeutic efficacy of a 6-day infusion of carboplatin, followed by X-irradiation with either 6 MV photons or synchrotron X-rays, tuned above the K-edge of Pt, for treatment of ...
Bobyk Laure, Edouard Magali, Deman Pierre, Rousseau Julia, Adam Jean-François, Ravanat Jean-Luc, Estève François, Balosso Jacques, Barth Rolf F, Elleaume Hélène   +9 more
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Comparison of Three Different Regimens of Oral Azithromycin in the Treatment of Acne Vulgaris

مجله دانشکده پزشکی اصفهان, 2012
Background: Acne vulgaris is a common skin disease that involves pilosebaceous units. Orally administered antibiotics are the most widely systemic therapeutics prescribed for the treatment of moderate to severe acne vulgaris.
Farahnaz Fatemi Naeini, Hooman Akrami
doaj