Results 101 to 110 of about 2,567,854 (328)

Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa, Jessica R. Landers, Nicholas S. Abend, Giulia M. Benedetti, Catherine J. Chu, Andrew T. Knox, Shavonne Massey, Steffany Moen, Andrea C. Pardo, Arnold Sansevere, Renée A. Shellhaas, Cameron Thomas, Tammy Tsuchida, Sonya Wang, Bo Zhang, Janet S. Soul   +15 more
wiley   +1 more source

THE EXPERIENCE OF USING LOW-TECHNOLOGY HYPOTHERMIA IN THE NEWBORN WITH SEVERE HYPOXIC ISCHAEMIC ENCEPHALOPATHY

Вестник анестезиологии и реаниматологии, 2017
Moderate therapeutic hypothermia is a promising technique for cerebral damage management aimed at the reduction of mortality and disability after hypoxic ischaemic encephalopathy.
A. A. Zadvornov, A. V. Golomidov, E. V. Grigor’ev   +2 more
doaj   +1 more source

Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]

, 2001
Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de,, Buwalda, Bauke,, Jong, Jelly G. de,, Koolhaas, Jaap M.,, Ruiter, Anne J.H. de,, Vegt, Bea J. van der,   +5 more
core   +1 more source

Maternal holding during therapeutic hypothermia for infants with neonatal encephalopathy is feasible

Acta paediatrica, 2019
Concerns for infant destabilisation often prohibit parental holding of infants during therapeutic hypothermia (TH). We assessed the feasibility of maternal holding during TH, as the inability to hold can impede bonding.
A. Craig, K. Deerwester, Leah Fox, J. Jacobs, Scott Evans   +4 more
semanticscholar   +1 more source

A contemporary simple risk score for prediction of severe acute kidney injury after heart transplantation

ESC Heart Failure, Volume 12, Issue 2, Page 1166-1175, April 2025.
A contemporary simple risk score for prediction of severe AKI after HT. Abstract Background The aim of this study was to develop a simple risk score to estimate severe acute kidney injury (AKI) risk based on a large contemporary heart transplantation (HT) cohort.
Shuangshuang Zhu, Weihua Qiao, Yixuan Wang, Ying Zhou, Yin Xu, Shijie Wang, Tian Xia, Guohua Wang, Si Chen, Jiawei Shi, Nianguo Dong   +10 more
wiley   +1 more source

Therapeutic hypothermia after out-of-hospital cardiac arrest - Should we keep platelets in mind?

Heart and Mind, 2017
Therapeutic hypothermia has been associated with an increase in thrombotic events, but this point has not been fully clarified. Most patients undergoing therapeutic hypothermia in a cardiac ICU receive antithrombotic treatment, usually in the context of ...
Rodolfo San Antonio, Eduardo Josué Flores-Umanzor, Margarida Pujol-López, Guillem Caldentey   +3 more
doaj   +1 more source

Therapeutic hypothermia: Applications in adults with acute ischemic stroke

Brain Circulation, 2019
The advent of mechanical thrombectomy and increasing alteplase use have transformed the care of patients with acute ischemic stroke. Patients with major arterial occlusions with poor outcomes now have a chance of returning to independent living in more ...
A. Kuczynski, A. Demchuk, M. Almekhlafi
semanticscholar   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Effects of therapeutic hypothermia on white matter injury from murine neonatal hypoxia-ischemia. [PDF]

, 2017
BackgroundTherapeutic hypothermia (TH) is the standard of care for neonates with hypoxic-ischemic encephalopathy, but it is not fully protective in the clinical setting.
Ferriero, Donna M, Koo, Elliot, Lee, Byong Sop, Sheldon, R Ann, Vexler, Zinaida S   +4 more
core   +2 more sources

Can we further optimize therapeutic hypothermia for hypoxic-ischemic encephalopathy?

Neural Regeneration Research, 2019
Perinatal hypoxic-ischemic encephalopathy is a leading cause of neonatal death and disability. Therapeutic hypothermia significantly reduces death and major disability associated with hypoxic-ischemic encephalopathy; however, many infants still ...
A. Davies, G. Wassink, L. Bennet, A. Gunn, J. Davidson   +4 more
semanticscholar   +1 more source