Results 81 to 90 of about 1,560,342 (283)

Thermoregulatory management for mild therapeutic hypothermia

, 2008
In recent years the use of mild therapeutic hypothermia as a means of neuroprotection has become an important concept for treatment after cerebral ischemic hypoxic injury.
Kimberger, Oliver, Kurz, Andrea
core   +1 more source

Host Cell Protein Challenges in Antibody Processing: Insights Into Persistence and Mitigation Strategies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Persistence of HCPs remains a major purification challenge in biopharmaceutical manufacturing with direct consequences for product quality, patient safety, and regulatory compliance. Over the last two decades, deeper insights into the mechanisms driving HCP persistence have clarified why certain proteins evade removal during purification ...
Younghoon Oh, Andrew Cooke, Harshal Soni, Susan Liu, Mamadou Bah, Brianna Bellis, Laura Smith, Michael Capaldi, Nicholas Levy, Erik Wilhelm, Kristopher Barnthouse   +10 more
wiley   +1 more source

therapeutic hypothermia [PDF]

Global Journal of Anesthesiology, 2015
Therapeutic hypothermia has been advocated for neuroprotection in cardiac arrest-induced encephalopathy, neonatal hypoxic-ischemic encephalopathy, traumatic brain injury, stroke, hepatic encephalopathy, and spinal cord injury, and as an adjunct to certain surgical procedures. In this review, we address physiological mechanism of hypothermia to mitigate
openaire   +3 more sources

Therapeutic Hypothermia after Cardiac Arrest

, 2016
The use of therapeutic hypothermia after cardiac arrest has been shown to reduce mortality and improve neurological outcomes in several randomized controlled trials.
Omairi, Ahmad
core  

Activation of mitochondrial STAT-3 and reduced mitochondria damage during hypothermia treatment for post-cardiac arrest myocardial dysfunction

, 2017
While therapeutic hypothermia improves the outcomes of individuals in cardiac arrest, the hemodynamic responses and mechanisms which underlie hypothermia-induced cardioprotection are not fully understood. Therefore, we investigated the mechanism by which
Huang, Chien-Hua;Tsai, Min-Shan;Chiang, Chih-Yen;Su, Yu-Jen;Wang, Tzung-Dau;Chang, Wei-Tien;Chen, Huei-Wen;Chen, Wen-Jone, 王宗道;張維典;黃建華;陳文鍾;陳惠文;蔡旼珊   +1 more
core   +1 more source

A contemporary simple risk score for prediction of severe acute kidney injury after heart transplantation

ESC Heart Failure, Volume 12, Issue 2, Page 1166-1175, April 2025.
A contemporary simple risk score for prediction of severe AKI after HT. Abstract Background The aim of this study was to develop a simple risk score to estimate severe acute kidney injury (AKI) risk based on a large contemporary heart transplantation (HT) cohort.
Shuangshuang Zhu, Weihua Qiao, Yixuan Wang, Ying Zhou, Yin Xu, Shijie Wang, Tian Xia, Guohua Wang, Si Chen, Jiawei Shi, Nianguo Dong   +10 more
wiley   +1 more source

Safety, Feasibility, and Hemodynamic Effects of Mild Hypothermia in Transcatheter Aortic Valve Replacement: The TAVR-CHILL Trial

, 2015
The safety, feasibility, and hemodynamic effects of mild hypothermia (MH) induced by transnasal cooling were studied in transcatheter aortic valve replacement (TAVR).
Bjursten, Henrik,, Hyllen, Snejana,, Harnek, Jan,, Nozohoor, Shahab,, Sparv, David,, Götberg, Matthias,, Lund University.   +6 more
core   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

THE EXPERIENCE OF USING LOW-TECHNOLOGY HYPOTHERMIA IN THE NEWBORN WITH SEVERE HYPOXIC ISCHAEMIC ENCEPHALOPATHY

Вестник анестезиологии и реаниматологии, 2017
Moderate therapeutic hypothermia is a promising technique for cerebral damage management aimed at the reduction of mortality and disability after hypoxic ischaemic encephalopathy.
A. A. Zadvornov, A. V. Golomidov, E. V. Grigor’ev   +2 more
doaj   +1 more source