The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley +1 more source
The Osmium Isotope Signature of Phanerozoic Large Igneous Provinces
Geophysical Monograph Series, Page 229-246., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Alexander J. Dickson +2 more
wiley +3 more sources
The Protective Role and Mechanism of Mild Therapeutic Hypothermia Protection on Brain Cells
Neuropsychiatric Disease and Treatment, 2023 Suixin Liang,1 Yunxing Ti,2 Xiuhong Li,1 Wenjia Zhou1 1Department of CICU, Shenzhen Children’s Hospital, Shenzhen City, Guangdong Province, People’s Republic of China; 2Department of Cardiothoracic Surgery, Shenzhen Children’s Hospital, Shenzhen City ...
Liang S, Ti Y, Li X, Zhou W
doaj
Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]
, 2001 Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de, +5 more
core +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon +5 more
wiley +1 more source
BMC MedicineBackground There is a lack of data regarding outcomes of therapeutic hypothermia in patients with acute myocardial infarction (AMI) complicated by out-of-hospital cardiac arrest (OHCA).
Oh-Hyun Lee +10 more
doaj +1 more source
Neuroprotective effect of therapeutic hypothermia versus standard care alone after convulsive status epilepticus: protocol of the multicentre randomised controlled trial HYBERNATUS [PDF]
, 2016 Convulsive status epilepticus (CSE) is a major medical emergency associated with a 50 % morbidity rate. CSE guidelines have recommended prompt management for many years, but there is no evidence to date that they have significantly improved practices or ...
Alain Cariou +6 more
core +1 more source
Long-term deficits in cortical circuit function after asphyxial cardiac arrest and resuscitation in developing rats [PDF]
, 2017 Cardiac arrest is a common cause of global hypoxic-ischemic brain injury. Poor neurologic outcome among cardiac arrest survivors results not only from direct cellular injury but also from subsequent long-term dysfunction of neuronal circuits.
Clark, Robert S.B. +5 more
core +2 more sources
Prenatal Diagnosis, EarlyView.ABSTRACT Objective The heterogeneity of fetal surgery has led to variability in the nature and frequency of fetal instability. Understanding these differences is critical for optimizing management. Methods We reviewed all fetal atrial septal interventions (FASI) and fetoscopic myelomeningocele (fMMC) repairs with fetal instability performed at our ...
Claire A. Naus +13 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Anthropogenic activities generate a significant amount of pollutants that are released into the environment, causing physiological and ecological disturbances. Among the xenobiotics present in aquatic ecosystems, numerous chemical and organic compounds have oxidative potential or are metabolized through oxidative processes, which may amplify ...
Natália Eduarda da Silva +6 more
wiley +1 more source