Results 151 to 160 of about 31,790 (233)

Sorafenib Restores Pentose Phosphate Pathway‐Related Redox Homeostasis via the c‐Raf/HSP90/G6PD Axis in Hepatic Ischemia‐Reperfusion Injury

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Proposed mechanism of middle‐dose sorafenib modulates redox homeostasis via c‐Raf/HSP90/G6PD axis to attenuate hepatic IRI. This study demonstrates that middle‐dose sorafenib mitigates hepatic IRI through the c‐Raf/HSP90/G6PD axis to enhance pentose phosphate pathway‐mediated antioxidant defense and redox homeostasis, thereby alleviating inflammatory ...
Fengqiang Gao   +13 more
wiley   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An   +4 more
wiley   +1 more source

Fatal Myocarditis Caused by Canine Parvovirus in a Litter of One‐Day‐Old German Shepherd Puppies: Molecular and Histopathological Findings

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Canine parvovirus infection resulted in acute fatal myocarditis in one‐day‐old German Shepherd puppies. Histopathology demonstrated lymphoplasmacytic myocarditis with intranuclear inclusion bodies, and PCR confirmed viral DNA in cardiac tissue. These findings indicate perinatal transmission and emphasise that CPV myocarditis remains a lethal threat to ...
Seyedhosein Jarolmasjed   +5 more
wiley   +1 more source

Sedative Effects of Dexmedetomidine and Ketamine or Dexmedetomidine and Midazolam on Tear Production, Ocular Perfusion Pressure and Pupil Diameter in Rabbits

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Sedative effects of intramuscular injection of dexmedetomidine and ketamine or dexmedetomidine and midazolam on tear production (TP), ocular perfusion pressure (OPP) and pupillary diameter (PD) in two groups of seven male New Zealand rabbits (G1 and G2, respectively).
Maryam Mohammadzadeh   +2 more
wiley   +1 more source

Real-World Therapeutic Hypothermia for Neonatal HIE: Neurodevelopmental Outcomes and Predictors. [PDF]

open access: yesActa Paediatr
Bedetti L   +23 more
europepmc   +1 more source

Effect of Intranasal Midazolam–Butorphanol Premedication on Sevoflurane Anaesthesia in Traumatised Buzzards (Buteo spp.)

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Intranasal midazolam–butorphanol premedication in traumatised buzzards (Buteo spp.) aims to provide safer sedation by minimising mask induction stress. This method significantly reduces sevoflurane requirements while maintaining stable cardiopulmonary parameters. It is a safe and practical alternative that enhances patient welfare and induction quality.
Can Nacar, Hatice Ozlem Nisbet
wiley   +1 more source

Home - About - Disclaimer - Privacy