Results 41 to 50 of about 7,496 (162)

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Pathogenic Role of Iron Deposition in Reticuloendothelial Cells during the Development of Chronic Hepatitis C

International Journal of Hepatology, 2013
Aim. Chronic hepatitis C (CHepC) is frequently associated with hepatic iron overload, yet mechanisms underlying iron-induced liver injury have not been elucidated.
Hironori Mitsuyoshi, Kohichiroh Yasui, Kanji Yamaguchi, Masahito Minami, Takeshi Okanoue, Yoshito Itoh   +5 more
doaj   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Application and clinical efficacy of red blood cell therapeutic apheresis in erythropoietic protoporphyria and hereditary hemochromatosis

Zhongguo shuxue zazhi
[Objective] To explore the application and clinical efficacy of red blood cell therapeutic apheresis in erythropoietic protoporphyria (EPP) and hereditary hemochromatosis (HH).
LIU Haoqiang, ZHAO Caihan, YUAN Qing, XIE Lixia, ZOU Yong, LU Ying   +5 more
doaj   +1 more source

Hyperviscosity syndrome revisited

Annals of Pediatric Cardiology, 2022
Secondary erythrocytosis occurs in cyanotic heart disease as a physiological response to chronic hypoxia, and this leads to hyperviscosity and various complications of the same.
Debasree Gangopadhyay, Mahua Roy, Somrita Laha, Debabrata Nandi, Rhitajyoti Sengupta, Amitabha Chattopadhyay   +5 more
doaj   +1 more source

Virtual Care of Acute Diverticulitis: A Phase I/II Randomised Clinical Feasibility Trial

ANZ Journal of Surgery, EarlyView.
Virtual care for acute uncomplicated diverticulitis appears feasible, safe and acceptable, with potential advantages over inpatient care, including superior patient‐reported experience. ABSTRACT Background Acute uncomplicated diverticulitis is commonly managed in hospital in Australia.
Phillip F. Yang, Philip Hay, Owen R. Hutchings, Rebecca A. Davis, Miranda Shaw, Shanmugam S. Somasundaram, Michael J. Solomon, Peter J. Lee, Kate E. McBride, Daniel Steffens, Kheng‐Seong Ng   +10 more
wiley   +1 more source

Treatment progress of phlebotomy for polycythemia vera

Zhongguo shuxue zazhi
Polycythemia vera (PV) is a BCR-ABL1-negative myeloproliferative neoplasm characterized by the proliferation of all three hematopoietic cell lines to varying degrees.
YANG Yanjie, QIN Ranran, HOU Ruiqin
doaj   +1 more source

Integrating novel therapeutic strategies in myeloproliferative neoplasms: Driving disease‐directed progress

British Journal of Haematology, EarlyView.
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo, Maria Georgiou, Donal P. McLornan, Claire N. Harrison   +3 more
wiley   +1 more source

Laboratory diagnostics and quality of blood collection [PDF]

Journal of Medical Biochemistry, 2015
Summary: Diagnostic blood samples collected by phlebotomy are the most common type of biological specimens drawn and sent to laboratory medicine facilities for being analyzed, thus supporting caring physicians in patient diagnosis, follow-up and/or ...
Lippi Giuseppe, Salvagno Gian Luca, Picheth Geraldo, Guidi Gian Cesare   +3 more
doaj  

A comparison of the results obtained with traditional phlebotomy and with therapeutic erythrocytapheresis in patients with erythrocytosis.

Blood transfusion = Trasfusione del sangue, 2007
Phlebotomy is the most commonly treatment used for erythrocytosis and polycythaemia. After the introduction in the medical practice of cell separators, erythrocytapheresis has been also introduced. The aim of the study was to compare the clinical results of the two kinds of treatment.We analysed 98 patients affected by different forms of erythrocytosis,
Sisto, Vecchio, Patrizia, Leonardo, Vittoria, Musuraca, Anna Rita, D'Ettoris, Walter, Geremicca   +4 more
openaire   +2 more sources