Results 51 to 60 of about 14,704 (250)

Testosterone therapy-induced erythrocytosis: can phlebotomy be justified?

Endocrine Connections
Erythrocytosis, or elevated hematocrit, is a common side effect of testosterone therapy (TTh) in male hypogonadism. Testosterone stimulates erythropoiesis through an initial rise in erythropoietin (EPO), the establishment of a new EPO/hemoglobin ‘set ...
Peter Bond, Tijs Verdegaal, Diederik L Smit   +2 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

The influence of hospitable design and service on patient responses [PDF]

, 2017
A study of 216 respondents examined a medical center environment’s influence on patient responses. A stimulus–organism–response (S-O-R) model was adapted to the theory that more hospitable healthcare servicescape elements will affect patients’ overall ...
Mody, Makarand, Suess, Courtney
core   +1 more source

Dried blood spot analysis in antidoping: Technical challenges, analytical advances, and future perspectives

Bulletin of the Korean Chemical Society, EarlyView.
Dried blood spot (DBS) analysis enables minimally invasive blood collection with strong analyte stability and simplified logistics, supporting anti‐doping applications beyond traditional matrices. Recent advances address hematocrit, volume variability, and matrix effects while expanding coverage to steroid esters, World Anti‐Doping Agency‐listed ...
Jihyun Yoon, Jiyeong Hong, Hanbin Oh, Chi Hwan Lee, Ki Hun Kim   +4 more
wiley   +1 more source

Therapeutic Erythrocytapheresis in the Initial Treatment of Hereditary Hemochromatosis

Acta Medica, 2012
Background: The current treatment of hereditary hemochromatosis (HH) consists of performing periodic whole blood phlebotomies. Erythrocytapheresis (EA) can remove up to three times more red blood cells per single procedure and could thus have a clinical ...
Vít Řeháček, Milan Bláha, Hana Jiroušová, Jitka Černohorská, Petr Papoušek   +4 more
doaj   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Improving sleep on the inpatient general, non‐stroke neurology service: A quasi‐experimental interventional trial

Journal of Hospital Medicine, EarlyView.
Abstract Background Hospitalized patients often experience poor sleep, which is associated with worse health outcomes, increased rates of delirium, and readmissions. Objective To improve overnight sleep for clinically stable general neurology patients at a single academic center.
Noor F. Shaik, Lydia Denison, G. M. Anya Venezia, Lovisa Ljungberg, Alexa Lebrón‐Cruz, David Resnick, Colleen Peachey, Carolyn Ziemba, Michael Buckley, Michael Karamardian, Patrick Z. Liu, Alan Napole, Jennifer Hong, Ruoheng Zeng, Connie Yu, Andrew Chan, Charles Bae, Laura Stein, Colin A. Ellis, Denise J. Xu   +19 more
wiley   +1 more source

Iron stores and coagulation parameters in patients with hypoxemic polycythemia secondary to chronic obstructive pulmonary disease: the effect of phlebotomies [PDF]

, 1997
This study was designed to determine the effects of phlebotomy on iron body contents and coagulation tests of COPD patients with polycythemia secondary to hypoxemia. Seventeen patients with COPD and hematocrits higher than 54 percent (mean Hct: 57 ± 0.49
Guerra, Celso Carlos de Campos, Jardim, José Roberto, Martinez, José Antônio Baddini, Nery, Luiz Eduardo   +3 more
core   +2 more sources

Low‐value glucose monitoring in noncritically ill hospitalized patients

Journal of Hospital Medicine, EarlyView.
Abstract Background Inpatient routine point‐of‐care glucose (POC‐G) monitoring is common given association of persistent hyperglycemia with increase in morbidity and mortality. However, some patients receive frequent fingerstick testing without needing insulin to reach glycemic targets.
Niloofar Latifi, Nestoras Mathioudakis, Mohammed S. Abusamaan, Megan M. Tschudy, Jianqiao Ma, Sarah Olson, Terra M. M. Jouaneh, Angie Yang, Daniel J. Brotman   +8 more
wiley   +1 more source

Hyperviscosity syndrome revisited

Annals of Pediatric Cardiology, 2022
Secondary erythrocytosis occurs in cyanotic heart disease as a physiological response to chronic hypoxia, and this leads to hyperviscosity and various complications of the same.
Debasree Gangopadhyay, Mahua Roy, Somrita Laha, Debabrata Nandi, Rhitajyoti Sengupta, Amitabha Chattopadhyay   +5 more
doaj   +1 more source