Results 161 to 170 of about 1,884,248 (304)

Le rôle de l’infirmière d’éducation thérapeutique dans un contexte de choix d’une méthode de dialyse : une étude qualitative

open access: yesSociologies, 2019
This article reports on how the nurse member of a therapeutic patient education (TPE) team positions herself in the decision-making process in which patients with chronic kidney disease have the possibility to choose a dialysis method and how they ...
Abdou Simon Senghor
doaj  

The influence of the environment on the patient-centered therapeutic relationship in physical therapy: a qualitative study. [PDF]

open access: yesArch Public Health, 2023
Morera-Balaguer J   +7 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

"INTEGRO INTEGRated Psychotherapeutic InterventiOn" on the Management of Chronic Pain in Patients with Fibromyalgia: The Role of the Therapeutic Relationship. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Pasini I   +8 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Le remède et ses usages historiques (1650-1820)

open access: yesHistoire, Médecine et Santé, 2012
Philip Rieder, François Zanetti
doaj   +1 more source

Grounded Therapy

open access: yesGrounded Theory Review: An International Journal
From the beginning of my experience with therapy, I saw many areas in which it was evident to me that the therapeutic process and the therapeutic relationship could be improved.
Odis Simmons
doaj  

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