Results 61 to 70 of about 1,089,381 (298)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Plan Analysis and the Motive-Oriented Therapeutic Relationship

open access: yes, 2019
Plan analysis is a case formulation approach that is independent of any particular school of therapy, and the concept of Motive-Oriented Therapeutic relationship is a prescriptive approach for how to manage constraints and possibilities related to the ...
Franz Caspar, Caspar, Franz
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Exploring the Three-Way Relationship in Therapeutic Work with Interpreters [PDF]

open access: yes, 2009
In a companion paper, we have argued that therapeutic work with interpreters has been viewed more negatively than is warranted, and that the inherent advantages of this way of engaging with the non English speaking client have been minimised or ignored ...
Thompson, Kate, Tribe, Rachel
core  

Measuring quality in the therapeutic relationship-Part 2: subjective approaches

open access: yes, 2010
Publisher version: http://qualitysafety.bmj.com/content/19/6/479 ...
Greenhalgh, T   +3 more
core   +1 more source

Measurement of Therapeutic Relationship in Physiotherapy

open access: yes, 2022
The ‘therapeutic relationship’ refers to the relationship between a patient and their healthcare provider, which is assumed to be therapeutic when the quality of the relationship affects the well-being and clinical outcomes of treatment. In physiotherapy,
McCabe, Erin
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Understanding and Assessing the Therapeutic Relationship in Community Mental Health Care

open access: yes, 2006
PhDThe clinician-patient relationship is at the core of community mental health care and impacts on outcome, but no instrument has been specifically developed for its assessmentE.
McGurie-Snieckus, Rebecca
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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