Results 71 to 80 of about 1,089,381 (298)

The culture of cancer and the therapeutic impact of qualitative research interviews

open access: yes, 2005
This paper is an account of the potential therapeutic impact of research interviews encountered while conducting a qualitative research study. Similarities between the therapeutic (or psychoanalytic) interview and the qualitative research interview are ...
Colbourne, L., Sque, M.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

EARLY AFFECT-CONFUSION: THE BORDERLINE BETWEEN DESPAIR AND RAGE - PART 1 OF A CASE STUDY TRILOGY

open access: yesInternational Journal of Integrative Psychotherapy, 2012
This three part case study illustrates the principles, theoretical concepts, and relational methods of Integrative Psychotherapy in the treatment of a client who continually experienced early affect-confusion and lived on a “borderline” between intense ...
Richard G. Erskine
doaj  

Culture and the therapeutic relationship: Perspectives from Chinese clients

open access: yes, 2007
Chinese people in the United Kingdom and United States underuse mental health services and, when they do seek help, may find that therapy does not meet their needs. In response to calls in the literature for naturalistic studies of therapy with people of
Jim, J, Pistrang, N
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Successful and Less Successful Psychotherapies Compared: Three Therapists and Their Six Contrasting Cases

open access: yesFrontiers in Psychology, 2019
Despite the general effectiveness of bona fide psychotherapies, the number of patients who deteriorate or fail to improve is still problematic. Furthermore, there is an increased awareness in the field that the therapists’ individual skills make a ...
Andrzej Werbart   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

'You have to learn these lessons sometime': Persuasion and therapeutic power relations in bestselling relationship manuals

open access: yes, 2010
Whilst self-help books have recently come under increased academic scrutiny, the power relations in the techniques they use in order to persuade, convince and convert their readers remain largely unexamined. This paper seeks to redress this omission, and
Hazleden, Rebecca
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Conversations with children : interviewer style in evidential and therapeutic interviews [PDF]

open access: yes, 1999
According to the Home Office Memorandum (1992), a rapport-building phase should always be included at the start of an interview with a child undertaken for criminal proceedings.
Thurlow, Katharine Jane
core  

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