Results 81 to 90 of about 7,872,411 (241)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Frontiers in PsychiatryBackgroundPsychotherapists need effective tools to monitor changes in the patient’s affective perception of the therapist and the therapeutic relationship during sessions to tailor therapeutic interventions and improve treatment outcomes. This study aims
Alberto Stefana +8 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
, 2005 The chapter opens with a brief description of therapeutic alliance assessment scales that may routinely be used in clinical practice and then research which highlights the strong relationship between the therapeutic alliance and outcome in marital and ...
Carr, Alan
core
THE PROCESS OF ANGER IN RELATIONSHIPS: A PERSONAL PERSPECTIVE I HATE YOU BECAUSE I NEED YOU
International Journal of Integrative Psychotherapy, 2012 Anger is a complicated affect. This paper reflects on how the therapeutic relation can help to explore its function as a psychological protection and the several issues that are underneath it. In this personal case study, the dyad mother-daughter is also
Angela Burper
doaj
Correlational study on the sense of humor and positive mental health in mental health professionals
Frontiers in Public HealthBackgroundMental health professionals require exceptional communication skills and the ability to maintain an empathetic and authentic attitude within the therapeutic relationship.
Sergi Piñar-Rodríguez +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
INTO THE LABYRINTH. A CASE STUDY OF A THERAPIST’S JOURNEY WITH AN ADULT SURVIVOR OF CHILDHOOD ABUSE
International Journal of Integrative Psychotherapy, 2014 This case study describes the therapeutic journey of a client who suffered serious sexual and physical abuse from toddlerhood to adolescence. It considers challenges and ethical issues in the therapeutic partnership with an abuse survivor, exploring the
Pamela Stocker
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source