Results 81 to 90 of about 1,089,381 (298)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The relationship between pharmacokinetic parameters of carbamazepine and therapeutic response in epileptic patients

, 2016
Introduction : The prescribed dose and carbamazepine plasma concentration to achieve the optimal therapeutic efficacy are highly variable from one patient to the other.
Sana Ben Amor, Aicha Laouani, Manel Nouira, Chahra Chbili, Anis Hassine, Saad Saguem, Sofiène Ben Ammou   +6 more
core   +1 more source

Therapeutic relationship and concordance of client- and clinician-rated motivational goals in treatment of people with psychosis: an exploratory study [PDF]

, 2018
Addressing motives determining behavior and experiences of people in treatment for psychosis could improve the therapeutic relationship. This pilot study explored the association between the concordance of clients’ and clinicians’ ratings of clients ...
Kupper, Zeno, Franz Caspar, Westermann, Stefan, Caspar, Franz, Zeno Kupper, Cavelti, Marialuisa, Marialuisa Cavelti, Stefan Westermann, Tschümperlin, Raphaela M., Raphaela M. Tschümperlin, Daniela Hubl, Hubl, Daniela   +11 more
core   +1 more source

Relationship-based practice and the creation of therapeutic change in long-term work: social work as a holding relationship

, 2022
Relationship-based practice has become a dominant theory through which what goes on between social workers and service users is understood. However, the presence of a relationship explains little and much more critical attention needs to be given to the ...
Leigh, Jadwiga, Cooner, Tarsem Singh, Disney, Tom, Singh Cooner, Tarsem, Beddoe, Liz, Cooner, Tarsem, Warwick, Lisa, Ferguson, Harry   +7 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

O envolvimento emocional para a equipe de enfermagem: realidade ou mito?

Revista Latino-Americana de Enfermagem
O presente tra balho tem como objetivo analisar o que os componentes da equipe de enfermagem de um hospital geral pensam sobre o envolvimento emocional em suas relações com o paciente.
Carmem Lúcia Alves Filizola, Noeli Marchioro Liston Andrade Ferreira   +1 more
doaj  

Comment les pères se représentent-ils leur engagement paternel et leur relation aux professionnel.le.s de la petite enfance ?

Enfances, Familles, Générations, 2023
Research framework: It is now well documented that fathers are more involved than before in the care and education of their children, even if these involvements are not monolithic and depend on many contextual and internal family factors.
Cecilia Scacchitti, Bernard Fusulier, Céline Mahieu   +2 more
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

MENTAL HEALTH PROFESSIONALS’ NON-CLINICAL ROLES AS INFORMED BY ATTACHMENT: A SYSTEMATIC REVIEW OF RESEARCH

Teaching and Supervision in Counseling
While attachment informs the quality of the therapeutic relationship, which is the basis of all therapeutic work for professional counselors and related mental health professionals (MHPs), less attention has been given to the role of attachment in MHPs ...
Jennifer L. Tipton , Casey A. Barrio Minton, Brittney N. R. Irion   +2 more
doaj   +1 more source

Psychometric Properties of Scale to Assess the Therapeutic Relationship—JapaneseVersion (STAR-J)

Frontiers in Psychiatry, 2019
Background: A good therapeutic relationship between patient and psychiatrist is vital for effective mental health care. However, no instruments to assess this relationship are available in Japan.
Asami Matsunaga, Asami Matsunaga, Sosei Yamaguchi, Utako Sawada, Utako Sawada, Takuma Shiozawa, Takuma Shiozawa, Chiyo Fujii   +7 more
doaj   +1 more source