Bayesian data assimilation to support informed decision-making in individualized chemotherapy [PDF]
, 2020 An essential component of therapeutic drug/biomarker monitoring (TDM) is to combine patient data with prior knowledge for model-based predictions of therapy outcomes.
de Wiljes, Jana +4 more
core +2 more sources
Liposomes as Tools to Improve Therapeutic Enzyme Performance
Pharmaceutics, 2022 The drugs concept has changed during the last few decades, meaning the acceptance of not only low molecular weight entities but also macromolecules as bioagent constituents of pharmaceutics.
Maria Eugénia Meirinhos Cruz +4 more
doaj +1 more source
Extracellular vesicles: Emerging tools as therapeutic agent carriers
Acta Pharmaceutica Sinica B, 2022 Extracellular vesicles (EVs) are secreted by both eukaryotes and prokaryotes, and are present in all biological fluids of vertebrates, where they transfer DNA, RNA, proteins, lipids, and metabolites from donor to recipient cells in cell-to-cell ...
Shan Liu +7 more
doaj +1 more source
New histone deacetylase inhibitors as potential therapeutic tools for advanced prostate carcinoma [PDF]
, 2008 The anti-epileptic drug valproic acid is also under trial as an anti-cancer agent due to its histone deacetylase (HDAC) inhibitory properties. However, the effects of valproic acid (VPA) are limited and concentrations required for exerting anti ...
Atmaca, Akin +8 more
core +1 more source
Components of cell-matrix linkage as potential new markers for prostate cancer [PDF]
, 2011 Prostate cancer is one of the most common tumor diseases worldwide. Often being non-aggressive, prostate tumors in these cases do not need immediate treatment.
Eble, Johannes Andreas, Navdaev, Alexey
core +2 more sources
Extracellular Vesicles: From Biomarkers to Therapeutic Tools
Biology, 2020 Intercellular communication is an essential hallmark of multicellular organisms and can be mediated through direct cell–cell contact or transfer of secreted molecules. In the last two decades, a third mechanism for intercellular communication has emerged
Simona Bernardi, Carolina Balbi
doaj +1 more source
Broad and potent cross clade neutralizing antibodies with multiple specificities in the plasma of HIV-1 subtype C infected individuals. [PDF]
, 2017 Broadly Cross clade Neutralizing (BCN) antibodies are recognized as potential therapeutic tools and leads for the design of a vaccine that can protect human beings against various clades of Human Immunodeficiency Virus (HIV).
Ashokkumar, Manickam +12 more
core +3 more sources
Immunoscintigraphy for therapy decision making and follow-up of biological therapies [PDF]
, 2016 With the availability of new biological therapies there is the need of more accurate diagnostic tools to noninvasively assess the presence of their targets.
Auletta, S. +6 more
core +2 more sources
Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation [PDF]
, 2018 During the 2017 Biennial meeting, the American Academy of Veterinary Pharmacology and Therapeutics hosted a 1‐day session on the influence of population variability on dose‐exposure‐response relationships. In Part I, we highlighted some of the sources of
Bailey +40 more
core +12 more sources
The pharmacological regulation of cellular mitophagy [PDF]
, 2017 Small molecules are pharmacological tools of considerable value for dissecting complex biological processes and identifying potential therapeutic interventions.
A Brunet +103 more
core +4 more sources