Results 11 to 20 of about 28,229 (283)

C9orf72-Related Neurodegenerative Diseases: From Clinical Diagnosis to Therapeutic Strategies

open access: yesFrontiers in Aging Neuroscience, 2022
Hexanucleotide expansion in C9orf72 has been related to several phenotypes to date, complicating the clinical recognition of these neurodegenerative disorders.
Stefania Zampatti   +7 more
doaj   +1 more source

Role of Fibroblast Growth Factor Receptor 2 in Pancreatic Cancer: Potential Target for New Therapeutic Approach? [PDF]

open access: yes, 2015
Fibroblast growth factors and their receptors play a key role in cell proliferation, migration and differentiation. Fibroblast growth factor receptor 2 (FGFR2) is involved in carcinogenesis and its altered expression has been shown in several tumors ...
Angeloni, Antonio   +2 more
core   +1 more source

Syncope: therapeutic approaches.

open access: yesJournal of the American College of Cardiology, 2009
Syncope is a common clinical problem characterized by transient, spontaneously self-terminating loss of consciousness with complete and prompt recovery; the cause is insufficiency of cerebral oxygen/nutrient supply most often due to a transient fall of systemic arterial pressure to levels below those tolerated by cerebrovascular autoregulation. Careful
Benditt, David G., Nguyen, John T.
openaire   +2 more sources

High potency of melaleuca alternifolia essential oil against multi-drug resistant gram-negative bacteria and methicillin-resistant staphylococcus aureus [PDF]

open access: yes, 2018
Purpose: Herein, an extended investigation of Tea tree oil (TTO) against a number of multi-drug resistant (MDR) microorganisms in liquid and vapor phases is reported.
Božović, Mijat   +7 more
core   +1 more source

Marine-Inspired Drugs and Biomaterials in the Perspective of Pancreatic Cancer Therapies

open access: yesMarine Drugs, 2022
Despite its low prevalence, pancreatic cancer (PC) is one of the deadliest, typically characterised as silent in early stages and with a dramatically poor prognosis when in its advanced stages, commonly associated with a high degree of metastasis.
Andreia S. Fernandes   +4 more
doaj   +1 more source

Development of an Ex Vivo Organ Culture Technique to Evaluate Probiotic Utilization in IBD [PDF]

open access: yes, 2016
The consistent technical and conceptual progress in the study of the microbiota has led novel impulse to the research for therapeutical application of probiotic bacteria in human pathologies, such as inflammatory bowel disease (IBD).
DELLE FAVE, Gianfranco   +3 more
core   +1 more source

Ferenczi’s Revolutionary Therapeutic Approach*

open access: yesThe American Journal of Psychoanalysis, 2017
Many of the revolutionary principles introduced by Ferenczi in his clinical practice have now been widely accepted especially in the field of trauma and trauma therapy. Examples of these innovative views include his emphasis on empathy as opposed to technical neutrality and his stress on the real conditions of child caring and family environmental ...
MUCCI, Clara   +3 more
openaire   +4 more sources

El Continuun causal del envejecimiento: la detección precoz de la demencia y el papel de los factores protectores y de riesgo

open access: yesActa Neurológica Colombiana, 2023
The prevalence of cognitive disorders and dementia increases with age and represents a high cost to society and health services. Some authors have suggested an ongoing process that leads from the cognitive impairments to dementia, with a presentation ...
Carolina Restrepo   +2 more
doaj   +2 more sources

Mitochondrial Diseases: Therapeutic Approaches

open access: yesBioscience Reports, 2007
Therapy of mitochondrial encephalomyopathies (defined restrictively as defects of the mitochondrial respiratory chain) is woefully inadequate, despite great progress in our understanding of the molecular bases of these disorders. In this review, we consider sequentially several different therapeutic approaches.
DiMauro S., Mancuso M.
openaire   +2 more sources

Nanodelivery Strategies for Skin Diseases with Barrier Impairment: Focusing on Ceramides and Glucocorticoids

open access: yesNanomaterials, 2022
The human epidermis has a characteristic lipidic composition in the stratum corneum, where ceramides play a crucial role in the skin barrier homeostasis and in water-holding capacity.
Cíntia Almeida   +3 more
doaj   +1 more source

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