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Pharmacists in clozapine clinics improving physical health monitoring [PDF]
Mental Health Clinician, 2022 Introduction: People living with schizophrenia have a higher rate of comorbid physical health diseases and compared with the general population die earlier due to these diseases.
Greg Spann, BPharm, GCert Psychiatric Therapeutics +2 more
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Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
Respiratory Research, 2021 Rationale αv integrins, key regulators of transforming growth factor-β activation and fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial cells (αvβ6) and fibroblasts (αvβ1) in fibrotic lungs.
Martin L. Decaris +27 more
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Effectiveness of Acceptance and Commitment Therapy in Reducing High-risk and Harmful Behaviors in Students [PDF]
مجله علوم پزشکی صدرا, 2023 Introduction: The prevalence of high-risk behaviors in young people is one of the concerns of societies. This study aimed to evaluate the effectiveness of Acceptance and Commitment therapy in reducing high-risk and harmful behaviors among high school ...
Zahra Alizadeh, Abbas Rohani
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Therapeutic effects of diosgenin on alveolar bone loss and apoptosis in diabetic rats with experimental periodontitis [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): The present study aims to evaluate the efficacy of administered diosgenin (DG) which has anti-oxidant and anti-inflammatory effects, on alveolar bone loss (ABL) and apoptosis in diabetic rats with periodontitis. Materials and Methods: Forty
Alper Kızıldağ +4 more
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Oncogenesis, 2023 Chimeric antigen receptor T-cell (CAR-T) therapy has demonstrated potent clinical efficacy in the treatment of hematopoietic malignancies. However, the application of CAR-T in solid tumors has been limited due in part to the expression of inhibitory ...
Zhao Chen +25 more
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A spoonful of sugar: the application of glycopolymers in therapeutics [PDF]
, 2011 Glycopolymers, synthetic polymers displaying carbohydrate moieties, have been linked to many potential applications at the biology–chemistry interface. One area that holds particular promise is the employment of glycopolymers as vehicles for therapeutics
Cameron, Neil R., Spain, Sebastian G.
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Journal of Neuroinflammation, 2021 Background Inflammation in the central nervous system (CNS) is observed in many neurological disorders. Nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO–sGC–cGMP) signaling plays an essential role in modulating neuroinflammation.
Susana S. Correia +16 more
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Pregabalin: a range of misuse-related unanswered questions [PDF]
, 2019 © 2019 The Authors.
Chiappini, Stephania, Schifano, Fabrizio
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Molecular Systems Biology, 2022 Enteric hyperoxaluria (EH) is a metabolic disease caused by excessive absorption of dietary oxalate leading to the formation of chronic kidney stones and kidney failure. There are no approved pharmaceutical treatments for EH.
David Lubkowicz +13 more
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Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]
, 2020 In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco +4 more
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