Results 1 to 10 of about 1,594,004 (375)
Pharmacists in clozapine clinics improving physical health monitoring [PDF]
Mental Health Clinician, 2022 Introduction: People living with schizophrenia have a higher rate of comorbid physical health diseases and compared with the general population die earlier due to these diseases.
Greg Spann, BPharm, GCert Psychiatric Therapeutics +2 more
doaj +1 more source
Macrophages in immunoregulation and therapeutics
Signal Transduction and Targeted Therapy, 2023 Macrophages exist in various tissues, several body cavities, and around mucosal surfaces and are a vital part of the innate immune system for host defense against many pathogens and cancers.
Shanze Chen +7 more
semanticscholar +1 more source
Chemistry, structure and function of approved oligonucleotide therapeutics
Nucleic Acids Research, 2023 Eighteen nucleic acid therapeutics have been approved for treatment of various diseases in the last 25 years. Their modes of action include antisense oligonucleotides (ASOs), splice-switching oligonucleotides (SSOs), RNA interference (RNAi) and an RNA ...
M. Egli, M. Manoharan
semanticscholar +1 more source
Engineering protein-based therapeutics through structural and chemical design
Nature Communications, 2023 Ebrahimi and Samanta review the key advances in the chemical and structural modification of proteins that have enabled their rise as indispensable tools in medicine and outline emerging protein engineering strategies that can potentially unlock ...
Sasha B. Ebrahimi, Devleena Samanta
semanticscholar +1 more source
NANOBODIES®: A Review of Generation, Diagnostics and Therapeutics
International Journal of Molecular Sciences, 2023 NANOBODY® (a registered trademark of Ablynx N.V) molecules (Nbs), also referred to as single domain-based VHHs, are antibody fragments derived from heavy-chain only IgG antibodies found in the Camelidae family.
Bo Jin +3 more
semanticscholar +1 more source
The American Journal of the Medical Sciences, 1905 n ...
Wilcox, Reynold Webb +1 more
openaire +2 more sources
CRISPR/Cas9 therapeutics: progress and prospects
Signal Transduction and Targeted Therapy, 2023 Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases by permanently correcting deleterious base mutations or disrupting disease-
Tianxiang Li +9 more
semanticscholar +1 more source
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
Respiratory Research, 2021 Rationale αv integrins, key regulators of transforming growth factor-β activation and fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial cells (αvβ6) and fibroblasts (αvβ1) in fibrotic lungs.
Martin L. Decaris +27 more
doaj +1 more source
The American Journal of The Medical Sciences, 1920 n ...
Lambert, Samuel W., Lieb, Charles C.
openaire +1 more source
Digital therapeutics from bench to bedside
npj Digital Medicine, 2023 As a new therapeutic technique based on digital technology, the commercialization and clinical application of digital therapeutics (DTx) are increasing, and the demand for expansion to new clinical fields is remarkably high.
Changwon Wang +2 more
semanticscholar +1 more source