Results 21 to 30 of about 1,064,547 (319)
Therapeutics Letter 124 provides results of the Therapeutics Initiative's fifth readership survey to evaluate perceptions of our academic unit and the impact of Therapeutics Initiative learning events.Medicine, Faculty ofAnesthesiology, Pharmacology and ...
Therapeutics Initiative (University of British Columbia)
core
Therapeutics Letter 127 discusses personal prescribing portraits as an innovative method for community-based physicians to monitor and evaluate the appropriateness of their prescribing practices.Medicine, Faculty ofAnesthesiology, Pharmacology and ...
Therapeutics Initiative (University of British Columbia)
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ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks +5 more
wiley +1 more source
Therapeutics Letter 122 is the second of two issues celebrating 25 years of The Therapeutics Initiative by highlighting key conclusions from the 120 issues of the Therapeutics Letter that have been published to date.Medicine, Faculty ofAnesthesiology ...
Therapeutics Initiative (University of British Columbia)
core
Therapeutics Letter 136 examines conflicts of interest in primary care and the pharmaceutical industry. Conclusions: Industry sponsorship of clinical trials can lead to biased conclusions, including exaggerated claims of efficacy and underestimation of ...
Therapeutics Initiative (University of British Columbia)
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Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications
Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators.
Ruiyin Guo +5 more
doaj +1 more source
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
Therapeutics Letter 9 reviews the recommendations published by The Therapeutics Initiative in our first year, including some updated information based on feedback which we have received from readers of the Therapeutics Letter.Medicine, Faculty ...
Therapeutics Initiative (University of British Columbia)
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Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a familial cardiac disease associated with ventricular arrhythmias and an increased risk of sudden cardiac death. Currently, there are no approved treatments that address the underlying
Iris Wu +31 more
doaj +1 more source
Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation
Pyroptosis is a proinflammatory form of cell death, mediated by membrane pore-forming proteins called gasdermins. Gasdermin pores allow the release of the pro-inflammatory cytokines IL-1β and IL-18 and cause cell swelling and cell lysis leading to ...
Fabian A. Fischer +2 more
doaj +1 more source

