Results 121 to 130 of about 9,958 (268)

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Bridging the gap: sex-specific differences in Huntington's disease. [PDF]

Orphanet J Rare Dis
Hemicker G, Schwarzová K, Labrecque S, Cerejo C, Carbone F, Peball M, Wimmer B, Mahlknecht P, Krismer F, Djamshidian A, Seppi K, Heim B.   +11 more
europepmc   +1 more source

The psychoactive effects of repeated ketamine infusions and their mechanistic role in the treatment of alcohol use disorder: Secondary analysis of a randomised controlled trial

Addiction, EarlyView.
Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy, Ananya Sarma, Bethan Marsh, Lorna Hardy, Meryem Grabski, Merve Mollaahmetoglu, Joshua Shotton, Shamhethan Bhaskaran, Anne Lingford‐Hughes, H. Val Curran, Celia Morgan, Will Lawn   +11 more
wiley   +1 more source

Examining New Mothers' Access to Zuranolone. [PDF]

Ochsner J
Simmers TJO, Galarneau DW.
europepmc   +1 more source

Adolescent cannabis use and psychological distress from 2013 to 2023: A population‐based study in Ontario, Canada

Addiction, EarlyView.
Abstract Background and aims Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. depression and anxiety symptoms); however, most studies have relied on 20th‐century data, when cannabis was significantly less potent than today.
André J. McDonald, Amanda Doggett, Susan J. Bondy, Ian Colman, Steven Cook, Hayley A. Hamilton, Paul Kurdyak, Scott T. Leatherdale, Daniel T. Myran, Jürgen Rehm, Christine M. Wickens, James MacKillop, Jillian Halladay   +12 more
wiley   +1 more source

Digital intervention mylovia improves sexual functioning in women with sexual dysfunction in randomized controlled trial. [PDF]

NPJ Digit Med
Blaszcyk W, Büttner M, Betz LT, Riepenhausen A, Jacob GA, Klein JP, Schröder J.   +6 more
europepmc   +1 more source

Changes over time in hallucinogen‐related emergency department visits in Ontario, Canada

Addiction, EarlyView.
Abstract Background and aims Recent increasing interest in hallucinogens has underscored the critical gaps in our understanding of their adverse health effects and healthcare usage over time. The current study aimed to examine changes in emergency department (ED) visit rates involving hallucinogens, clinical outcomes of visits and the characteristics ...
Daniel T. Myran, Rachael MacDonald‐Spracklin, Alexander R. Levesque, Michael Pugliese, Jess G. Fiedorowicz, André J. McDonald, Joshua D. Rosenblat, Ian Colman, Josephine Zein, Marco Solmi   +9 more
wiley   +1 more source

Off-label drug use in children and adolescents treated with antidepressants and antipsychotics: results from a prospective multicenter trial. [PDF]

Child Adolesc Psychiatry Ment Health
Taurines R, Gerlach M, Correll CU, Plener PL, Malzahn U, Heuschmann P, Scherf-Clavel M, Rock H, Briegel W, Fleischhaker C, Häge A, Hellenschmidt T, Imgart H, Kaess M, Karwautz A, Kölch M, Reitzle K, Renner TJ, Reuter-Dang SY, Rexroth C, Schulte-Körne G, Theisen F, Tini E, Wewetzer C, Fekete S, Romanos M, Egberts KM.   +26 more
europepmc   +1 more source

Monitoring outcomes of substance use disorder among healthcare professionals in Utah: A retrospective study of the professionals health program

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Substance use disorders (SUD) among healthcare professionals threaten both patient safety and workforce stability. Professional health programs (PHPs) aim to support recovery and safe practice reentry, yet outcomes for non‐physician professionals remain underexplored. This study assessed return to use and professional
Mubo O. Olufemi, Lisa J. Merlo, Melissa Cheng, Hongwei Zhao, Justin Yang, Matthew S. Thiese   +5 more
wiley   +1 more source

Voice of Asia: Provision of Patient‐Centered Care in Oral Cavity Cancer: A Qualitative Study With Patients, Caregivers, and Healthcare Professionals in Five Asia‐Pacific Regions

Asia-Pacific Journal of Clinical Oncology, EarlyView.
The study identified key barriers to optimal patient‐centered care, including delayed diagnosis due to awareness and stigma‐related barriers among patients and caregivers, and opportunities to enhance multidisciplinary coordination. Resource limitations impacted nursing and psychosocial support, while access to support care varied across regions.
Edwin Pun Hui, Puma Sundaresan, Hye Ryun Kim, Khoi Tuan Nguyen, Tracey E Nicholls, Hai‐Ling Teng, Yu‐Chung Li, Ying Jie Yew, Regina Gowindah, Con Stylianou, Pei‐Jen Lou   +10 more
wiley   +1 more source