Results 151 to 160 of about 9,958 (268)

Effectiveness of Long-Acting Injectable Antipsychotics Versus Oral Antipsychotics in People With Bipolar Disorder: A Systematic Review and Meta-Analysis of Observational Studies: Efficacité des antipsychotiques injectables à action prolongée par rapport aux antipsychotiques oraux chez les personnes atteintes de troubles bipolaires : revue systématique et méta-analyse d'études observationnelles. [PDF]

Can J Psychiatry
Wagner E, Katyal S, Lee IO, Tasnim S, El Wadia H, Mortazavi M, García-Carmona JA, Hasan A, Colman I, Taipale H, Tiihonen J, Correll CU, Højlund M, Solmi M.   +13 more
europepmc   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

British Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays. [PDF]

Alzheimers Dement
van der Veere PJ, van Harten AC, van Maurik IS, Teunissen CE, Barkhof F, Vos SJB, Froelich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Frisoni GB, Spiru L, Freund-Levi Y, Wallin ÅK, Hampel H, Tsolaki M, Kłoszewska I, Mecocci P, Vellas B, Lovestone S, Galluzzi S, Herukka SK, Santana I, Baldeiras I, de Mendonca A, Silva D, Chetelat G, Poisnel G, Visser PJ, Johnson SC, Stormrud E, Hansson O, Palmqvist S, Piñol-Ripoll G, Alzheimer's Disease Neuroimaging Initiative, Berkhof J, van der Flier WM.   +38 more
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Treatment for co-occurring posttraumatic stress disorder and substance use disorders among veterans and civilians: A test of causally moderated comparative effectiveness. [PDF]

Psychol Trauma
Blakey SM, Morgan-López AA, Kline AC, Shevorykin A, Norman SB, Killeen TK, Back SE, Simpson TL, Saavedra LM, Petrakis IL, Hien DA.   +10 more
europepmc   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Creativity and transition to bipolar disorder: a prospective analysis from the early-bipolife study. [PDF]

Int J Bipolar Disord
Michaelis E, Bauer M, Bechdolf A, Bermpohl F, Berndt C, Bröckel-Bundt KL, Burkhardt E, Correll CU, Dannlowski U, Falkenberg I, Fallgatter AJ, Fusar-Poli P, Hadji S, Jansen A, Juckel G, Kircher T, Kittel-Schneider S, Krüger-Özgürdal S, Lambert M, Leopold K, Maicher B, Matura S, Mennigen E, Mikolas P, Reif A, Ritter P, Sauer C, Stamm T, Martini J, Pfennig A.   +29 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Trends in non-pharmacological treatment for insomnia: A nationwide study. [PDF]

PLoS One
Choi M, Lee J, Lee J, Lee S, Lee E, Shin J.   +5 more
europepmc   +1 more source

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source