Results 31 to 40 of about 1,429,081 (399)
Molecular Systems Biology, 2022 Enteric hyperoxaluria (EH) is a metabolic disease caused by excessive absorption of dietary oxalate leading to the formation of chronic kidney stones and kidney failure. There are no approved pharmaceutical treatments for EH.
David Lubkowicz +13 more
doaj +1 more source
Breast cancer related lymphedema and surgical treatment [PDF]
Precision and Future Medicine, 2020 Lymphedema is a chronic, progressive and debilitating disease. This review article focuses on surgical treatment of breast cancer-related lymphedema especially in perspectives of microsurgical options.
Byung-Joon Jeon, David W. Chang
doaj +1 more source
Engineering the next generation of cell-based therapeutics
Nature reviews. Drug discovery, 2022 Cell-based therapeutics are an emerging modality with the potential to treat many currently intractable diseases through uniquely powerful modes of action.
C. Bashor +4 more
semanticscholar +1 more source
Tau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease [PDF]
, 2015 ACKNOWLEDGMENTS We thank patients and their caregivers for their participation in the study and are indebted to all the investigators involved in the study, particularly Drs. Douglas Fowlie and Donald Mowat for their helpful contributions to the clinical
Bentham, Peter +7 more
core +1 more source
Insulin Resistance: From Mechanisms to Therapeutic Strategies [PDF]
Diabetes & Metabolism Journal, 2022 Insulin resistance is the pivotal pathogenic component of many metabolic diseases, including type 2 diabetes mellitus, and is defined as a state of reduced responsiveness of insulin-targeting tissues to physiological levels of insulin.
Shin-Hae Lee +2 more
doaj +1 more source
Journal for Person-Oriented Research, 2019 The conventional view on interventions as mechanistically causing interchangeable clients to get better has come under attack. Group-based and linear approaches fall short in adequately describing the idiosyncratic and dynamic nature of treatment processes.
Guido Strunk, Anna Lichtwarck-Aschoff
openaire +5 more sources
Portuguese Journal of Public Health, 2022 Dysphagia is frequent after stroke, and it increases the risk of respiratory infection, dehydration and malnutrition, resulting in worse outcomes. Different clinical guidelines present recommendations for the assessment and management of dysphagia in ...
Isabel de Jesus Oliveira +5 more
doaj +1 more source
Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs. [PDF]
, 2018 Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Gervay-Hague, Jacquelyn +2 more
core +1 more source
Digital Therapeutics for Mental Health: Is Attrition the Achilles Heel? [PDF]
arXiv, 2022 Digit therapeutics are novel software devices that clinicians may utilize in delivering quality mental health care and ensuring positive outcomes. However, uptake of digital therapeutics and clinically tested software-based programs remains low. This article presents possible reasons for attrition and low engagement in clinical studies investigating ...
arxiv
The current landscape of nucleic acid therapeutics
Nature Nanotechnology, 2021 The increasing number of approved nucleic acid therapeutics demonstrates the potential to treat diseases by targeting their genetic blueprints in vivo.
J. Kulkarni +6 more
semanticscholar +1 more source