Results 31 to 40 of about 734,599 (256)
Tracking Short-Term Temporal Linguistic Dynamics to Characterize Candidate Therapeutics for COVID-19 in the CORD-19 Corpus [PDF]
arXiv, 2021 Scientific literature tends to grow as a function of funding and interest in a given field. Mining such literature can reveal trends that may not be immediately apparent. The CORD-19 corpus represents a growing corpus of scientific literature associated with COVID-19.
arxiv
Some Perspectives on Network Modeling in Therapeutic Target Prediction [PDF]
Biomedical Engineering and Computational Biology, 5, 17-24, 2013, 2013 Drug target identification is of significant commercial interest to pharmaceutical companies, and there is a vast amount of research done related to the topic of therapeutic target identification. Interdisciplinary research in this area involves both the biological network community and the graph algorithms community. Key steps of a typical therapeutic
arxiv +1 more source
Cell Therapy for Type 1 Diabetes [PDF]
, 2014 Acknowledgements The work described in this review was supported by a grant from the MRC. K.R.M. is supported by a fellowship from the Scottish Translational Medicines and Therapeutics Initiative through the Wellcome Trust.Peer reviewedPublisher ...
Docherty, H. M. +3 more
core +1 more source
Frontiers in MicrobiomesThe recent FDA approvals of Rebyota™ and Vowst™ represent landmark milestones within the burgeoning field of live microbiota-based products. Future microbiota-based treatment approaches also hold significant promise for treating patients with a myriad of
Microbiome Therapeutics Innovation Group +1 more
doaj +1 more source
Targeting STAT3 in Cancer with Nucleotide Therapeutics. [PDF]
, 2019 Signal transducer and activator of transcription 3 (STAT3) plays a critical role in promoting the proliferation and survival of tumor cells. As a ubiquitously-expressed transcription factor, STAT3 has commonly been considered an "undruggable" target for ...
Grandis, Jennifer R +3 more
core +2 more sources
Cannabidiol and Terpene Formulation Reducing SARS-CoV-2 Infectivity Tackling a Therapeutic Strategy
Frontiers in Immunology, 2022 In late 2019, COVID-19 emerged in Wuhan, China. Currently, it is an ongoing global health threat stressing the need for therapeutic compounds. Linking the virus life cycle and its interaction with cell receptors and internal cellular machinery is key to ...
Susana Santos +27 more
doaj +1 more source
Therapeutic target discovery using Boolean network attractors: improvements of kali [PDF]
Royal Society Open Science, The Royal Society, 2018, 5 (2), 2016 In a previous article, an algorithm for identifying therapeutic targets in Boolean networks modeling pathological mechanisms was introduced. In the present article, the improvements made on this algorithm, named kali, are described. These improvements are i) the possibility to work on asynchronous Boolean networks, ii) a finer assessment of therapeutic
arxiv +1 more source
RNA interference approaches for treatment of HIV-1 infection. [PDF]
, 2015 HIV/AIDS is a chronic and debilitating disease that cannot be cured with current antiretroviral drugs. While combinatorial antiretroviral therapy (cART) can potently suppress HIV-1 replication and delay the onset of AIDS, viral mutagenesis often leads to
Bobbin, Maggie L +2 more
core +1 more source
General practice – a fertile lagoon in the ocean of medical knowledge
Scandinavian Journal of Primary Health Care, 2021 General practitioners (GPs) often find that linear, deductive knowledge does not provide a sufficient map for clinical management. But experience, accompanied by enduring familiarity with individual patients, may offer unique complementary skills to ...
Kirsti Malterud, Harald Kamps
doaj +1 more source
Frontiers in Immunology, 2021 The unprecedented 2015–2016 Zika outbreak in the Americas sparked global concern and drove the rapid deployment of vaccine and therapeutic countermeasures against this re-emerging pathogen.
Vincent Dussupt +6 more
doaj +1 more source