Results 31 to 40 of about 1,553,588 (375)

Therapeutic Chaos [PDF]

Journal for Person-Oriented Research, 2019
The conventional view on interventions as mechanistically causing interchangeable clients to get better has come under attack. Group-based and linear approaches fall short in adequately describing the idiosyncratic and dynamic nature of treatment processes.
Guido Strunk, Anna Lichtwarck-Aschoff
openaire   +5 more sources

Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]

, 2012
The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R, Doak, Allison, Durrant, Jacob D, Keränen, Henrik, McCammon, J Andrew, Ratnam, Joseline, Rogers, Kathleen E   +6 more
core   +1 more source

An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria

Molecular Systems Biology, 2022
Enteric hyperoxaluria (EH) is a metabolic disease caused by excessive absorption of dietary oxalate leading to the formation of chronic kidney stones and kidney failure. There are no approved pharmaceutical treatments for EH.
David Lubkowicz, Nicholas G Horvath, Michael J James, Pasquale Cantarella, Lauren Renaud, Christopher G Bergeron, Ron B Shmueli, Cami Anderson, Jian‐Rong Gao, Caroline B Kurtz, Mylene Perreault, Mark R Charbonneau, Vincent M Isabella, David L Hava   +13 more
doaj   +1 more source

Cannabidiol and Terpene Formulation Reducing SARS-CoV-2 Infectivity Tackling a Therapeutic Strategy

Frontiers in Immunology, 2022
In late 2019, COVID-19 emerged in Wuhan, China. Currently, it is an ongoing global health threat stressing the need for therapeutic compounds. Linking the virus life cycle and its interaction with cell receptors and internal cellular machinery is key to ...
Susana Santos, Susana Santos, Pedro Barata, Pedro Barata, Adilia Charmier, Adilia Charmier, Inês Lehmann, Suzilaine Rodrigues, Matteo M. Melosini, Patrick J. Pais, Patrick J. Pais, André P. Sousa, André P. Sousa, André P. Sousa, Catarina Teixeira, Catarina Teixeira, Catarina Teixeira, Inês Santos, Inês Santos, Inês Santos, Ana Catarina Rocha, Ana Catarina Rocha, Pilar Baylina, Pilar Baylina, Pilar Baylina, Ruben Fernandes, Ruben Fernandes, Ruben Fernandes   +27 more
doaj   +1 more source

Immunopathogenesis of rheumatoid arthritis [PDF]

, 2017
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that
Ahmed, Ai, Ai, Anzilotti, Arend, Astorri, Benham, Bombardieri, Bottini, Bottini, Byng-Maddick, Catrina, Catrina, Charles-Schoeman, Christophorou, Corsiero, Croft, de Aquino, de Hair, Deane, Dennis, Diarra, Ekwall, El-Gabalawy, Ferreira, Filer, Firestein, Firestein, Firestein, Firestein, Firestein, Fonseca, Franz, Gary S. Firestein, Genovese, Hammaker, Harre, Hill, Horiuchi, Huber, Iain B. McInnes, Joosten, Juarez, Kaminsky, Karouzakis, Kelly, Kiener, Kim, Kinslow, Kirschmann, Klarenbeek, Konig, Konig, Krishnadas, Krishnamurthy, Källberg, Langley, Law, Lee, Lefèvre, Linn-Rasker, Liu, Lubberts, Lundström, Makrygiannakis, Matsumoto, McInnes, McInnes, McInnes, McInnes, McKellar, Miossec, Mydel, Müller-Ladner, Nakamachi, Nakano, Nakano, Nam, Okada, Pap, Perlman, Pitzalis, Randen, Rawlings, Raychaudhuri, Raza, Reynisdottir, Reynisdottir, Robertson, Rodríguez-Carrio, Rombouts, Rossetti, Scally, Scher, Schiff, Shi, Shi, Smolen, Smolen, Snir, Sokolove, Stanczyk, Suzuki, Tan, Tran, Tsaprouni, van Beers, van der Helm-van Mil, Vassallo, Wang, Wegner, Weyand, Yamamoto, Yang, Zhang, Zvaifler   +115 more
core   +1 more source

mRNA-based therapeutics: powerful and versatile tools to combat diseases

Signal Transduction and Targeted Therapy, 2022
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide range of incurable diseases. Recent rapid advances in biotechnology and molecular medicine have enabled the production of almost any functional protein/peptide in the ...
Shugang Qin, Xiaoshan Tang, Yuting Chen, Ke-Ke Chen, Na Fan, Wen Xiao, Qian Zheng, Guohong Li, Yuqing Teng, Min Wu, Xiangrong Song   +10 more
semanticscholar   +1 more source

Avulsion injuries: an update on radiologic findings [PDF]

Yeungnam University Journal of Medicine, 2021
Avulsion injuries result from the application of a tensile force to a musculoskeletal unit or ligament. Although injuries tend to occur more commonly in skeletally immature populations due to the weakness of their apophysis, adults may also be subject to
Changwon Choi, Sun Joo Lee, Hye Jung Choo, In Sook Lee, Sung Kwan Kim   +4 more
doaj   +1 more source

THERAPEUTICS [PDF]

The American Journal of the Medical Sciences, 1897
n ...
openaire   +3 more sources

Metabolic Implications of Oxidative Stress and Inflammatory Process in SARS-CoV-2 Pathogenesis: Therapeutic Potential of Natural Antioxidants

Frontiers in Cellular and Infection Microbiology, 2021
COVID-19 is a zoonotic disease with devastating economic and public health impacts globally. Being a novel disease, current research is focused on a clearer understanding of the mechanisms involved in its pathogenesis and viable therapeutic strategies ...
Gilead Ebiegberi Forcados, Aliyu Muhammad, Olusola Olalekan Oladipo, Sunday Makama, Clement Adebajo Meseko   +4 more
doaj   +1 more source

Implantable cardiac devices in geriatric patients: a primer for primary and geriatric physicians [PDF]

Reviews in Cardiovascular Medicine, 2021
In the next 20 years, the percentage of people older than 65 years of age in the United States is expected to double. Heart disease is the leading cause of mortality in developed nations, including the United States.
Farah Wani, Rawan Amir, Michael Aljadah, Michael Albosta, Jean Claude Guidi, Jagmeet Singh, Khalil Kanjwal, Asim Kichloo   +7 more
doaj   +1 more source