Results 121 to 130 of about 2,771,868 (291)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Witnessing Self-Affirming Moments in Persons with Dementia While Interacting with Therapy Dogs: A Case Report

Animals
Individuals, families, and communities are impacted by Alzheimer’s disease and other dementias worldwide. In Canada and elsewhere, family members commonly see loved ones living with dementia experience difficult moments, including anxiety, stress, and ...
Carolyn Brooks, Colleen A. Dell, Darlene Chalmers, Ben D. B. Carey   +3 more
doaj   +1 more source

Megacolon secondary to autonomic ganglioneuritis in a dog [PDF]

, 2001
Summary: A case of megacolon secondary to autonomic ganglioneuritis in a dog is described. Despite medical management with enemas, cisapride, and lactulose, the dog developed a faecal obstruction, requiring surgical intervention.
Nicholls, P.K., Gregory, S.P., Petrus, D.J.   +2 more
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

The Introduction of a ‘Therapy Dog’/‘Engagement Dog’ to Support the Work of the Youth Advisor [PDF]

, 2011
The Youth Advisor (Lisa Howarth) currently works to support young people up to 25 years of age to have the best possible learning experience whilst studying at CIT.
Lisa Howarth
core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Animal Assisted Therapy for Children with Autism

International Journal of Child Development and Mental Health, 2017
The inclusion of animals in therapeutic activities, known as animal-assisted therapy, can be used as a treatment practice for people with autism spectrum disorder (ASD).
See Ching Mey
doaj  

A Commentary about Lessons Learned: Transitioning a Therapy Dog Program Online during the COVID-19 Pandemic. [PDF]

Animals (Basel), 2021
Dell C, Williamson L, McKenzie H, Carey B, Cruz M, Gibson M, Pavelich A.   +6 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Null effects of therapy dog interaction on adolescent anxiety during a laboratory-based social evaluative stressor. [PDF]

Anxiety Stress Coping, 2021
Mueller MK, Anderson EC, King EK, Urry HL.   +3 more
europepmc   +1 more source