Results 101 to 110 of about 4,145,262 (262)

Optimizing Bisphosphonate Therapy in Oncology

open access: yesThe Oncologist, 2004
The role of bisphosphonates in the management of bone metastases is ...
openaire   +1 more source

On optimizing therapies, Orai, and ORNs [PDF]

open access: yesJournal of General Physiology, 2013
This month’s installment of Generally Physiological considers individualized therapeutic strategies to treat the congenital heart condition long QT syndrome (LQTS), determination of the crystal structure of the Orai calcium channel, and nonsynaptic communication between olfactory receptor neurons (ORNs) in insect sensilla.
openaire   +2 more sources

Comparison of responsibilities of occupational therapy practitioners in school-based practice

open access: yes, 2011
"Originally Published February 2010--Revised March 2011"--P. [1]; "Published February 2010"--P. [2]

core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Optimization of therapy in outpatients with chronic lumbago

open access: yesНеврология, нейропсихиатрия, психосоматика, 2014
Lumbago is one of the most common lower back pain syndromes in medical practice, which is benign in the vast majority of cases and caused by spinal osteochondrosis, injury, and muscle strain or spasm.
A. A. Averchenkova
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Equivalent-Uniform-Dose Optimization for Spatially Fractionated Radiation Therapy

open access: yesTechnology in Cancer Research & Treatment
Background Spatially fractionated radiotherapy (SFRT) intentionally creates spatially-modulated peak-valley dose patterns for improving the tumor control or/and the sparing of organs at risk, compared to conventional radiotherapy (CONV).
Ya-Nan Zhu PhD   +3 more
doaj   +1 more source

Improvements on the planning and delivery of intensity-modulated arc therapy [PDF]

open access: yes, 2010
In the past decade, intensity-modulated radiation therapy (IMRT) has taken a significant step towards dose conformality and has now become a standard radiotherapy technique in the clinic.
Tang, G.
core  

Gene Therapy for Allergic Diseases

open access: yes, 2010
Allergic diseases, such as allergic asthma, allergic rhinitis, atopic dermatitis, conjunctivitis, urticaria, food allergy, and/or anaphylaxis, are associated with the skewing of immune responses towards a T helper 2 ( TH2) phenotype, resulting in ...
莊雅惠;楊曜旭;江伯倫   +1 more
core   +1 more source

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