Results 81 to 90 of about 4,145,262 (262)

Hemodynamic benefit of rest and exercise optimization of cardiac resynchronization therapy

open access: yes, 2014
The optimal method of cardiac resynchronization therapy (CRT) optimization is as yet unknown. We sought to investigate the responses of optimization at rest and on exercise.
Leano, R   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

In‐Depth Analysis of the Necessity and Optimization Strategies for Adjuvant Radiotherapy Following Neoadjuvant Immunotherapy in the New Era of Esophageal Cancer Treatment

open access: yesCancer Innovation
As immunotherapy rises to prominence in cancer treatment, the therapeutic approach to esophageal cancer is undergoing significant transformations. This review emphasizes the necessity and optimization pathways for adjuvant postoperative radiotherapy ...
Guohui Liu   +3 more
doaj   +1 more source

What's in a name? : titles used in diversional therapy

open access: yes, 2020
After being involved in numerous discussions and debates over decades a question that is constantly asked by people in our field of practice is what title should we use?
Alford, Stewart (R19505)   +1 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Optimization of Nonspherical Gold Nanoparticles for Photothermal Therapy

open access: yesApplied Sciences, 2019
Previous investigations devoted to the optimization of nonspherical gold nanoparticles for photothermal therapy (PTT) encountered two issues, namely, the appropriate selection of objective functions and the processing of particle random orientations.
Paerhatijiang Tuersun   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Optimizing adherence to antiretroviral therapy

open access: yesThe Indian Journal of Medical Research, 2011
HIV has now become a manageable chronic disease. However, the treatment outcomes may get hampered by suboptimal adherence to ART. Adherence optimization is a concrete reality in the wake of 'universal access' and it is imperative to learn lessons from various studies and programmes.
Sahay, Seema   +2 more
openaire   +2 more sources

OT outlook (Online); OT newsletter

open access: yes, 2005
Electronic coverage as of Dec. 30, 2003: Vol. 1, no. 1 (spring 2001)-; Description based on: Vol. 2, issue 1 (winter 2003); title from caption (viewed Dec.
Ohio Occupational Therapy, Physical Therapy, and Athletic Trainers Board. Occupational Therapy Section.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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