Results 21 to 30 of about 868 (155)

Clinical, dosimetric, and reporting considerations for Y-90 glass microspheres in hepatocellular carcinoma: updated 2022 recommendations from an international multidisciplinary working group [PDF]

, 2022
International audiencePurpose In light of recently published clinical reports and trials, the TheraSphere Global Dosimetry Steering Committee (DSC) reconvened to review new data and to update previously published clinical and dosimetric recommendations ...
Herman, Joseph M., Salem, Riad, Lam, Marnix, Chiesa, Carlo, Sze, Daniel Y., Herman, Joseph M, Padia, Siddharth A, Kim, Edward, Padia, Siddharth A., Fowers, Kirk, Sze, Daniel Y, Sangro, Bruno, Kappadath, S. Cheenu, Kappadath, S Cheenu, Leung, Thomas, Garin, Etienne, Haste, Paul, Toskich, Beau   +17 more
core   +1 more source

Selective internal radiation therapies for unresectable early-, intermediate- or advanced-stage hepatocellular carcinoma: systematic review, network meta-analysis and economic evaluation

Health Technology Assessment, 2020
Background: Hepatocellular carcinoma is the most common type of primary liver cancer. Treatment choice is dependent on underlying liver dysfunction and cancer stage.
Matthew Walton, Ros Wade, Lindsay Claxton, Sahar Sharif-Hurst, Melissa Harden, Jai Patel, Ian Rowe, Robert Hodgson, Alison Eastwood   +8 more
doaj   +1 more source

Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez, Armeen Mahvash, James P. Long, Marnix G. E. H. Lam, S. Cheenu Kappadath   +4 more
wiley   +1 more source

Radiolabeled Nanocarriers as Theranostics—Advancement from Peptides to Nanocarriers

Small, Volume 18, Issue 25, June 23, 2022., 2022
Endogenous radiotherapy generally shows a favorable safety profile, however, it is limited by the dose that can be injected without affecting critical organs. This review offers important information and suggestions regarding the field of radio‐nanomedicine, which focuses on the use of nanocarriers for the delivery of radionuclide in order to improve ...
Prachi Desai, Rahul Rimal, Sabri E. M. Sahnoun, Felix. M. Mottaghy, Martin Möller, Agnieszka Morgenroth, Smriti Singh   +6 more
wiley   +1 more source

ArTisaN trial protocol: a single Centre, open-label, phase II trial of the safety and efficacy of TheraSphere selective internal radiation therapy (SIRT) in the treatment of inoperable metastatic (liver) neuroendocrine neoplasia (NENs)

BMC Cancer, 2022
Background Neuroendocrine neoplasias (NENs) are a rare type of malignancy that arise from the cells of the neuroendocrine system. Most patients present with advanced, unresectable disease, typically with metastases to the liver.
Rohini Sharma, Susanna Slater, Joanne Evans, Maria Martinez, Caroline Ward, Hooshang Izadi, Florian Wernig, Rob Thomas   +7 more
doaj   +1 more source

Immunotherapy and Transarterial therapy of HCC: What the interventional radiologist needs to know about the changing landscape of HCC treatment?

Journal of Medical Imaging and Radiation Oncology, Volume 66, Issue 4, Page 478-482, June 2022., 2022
Abstract Hepatocellular carcinoma (HCC) is the fourth most common cancer worldwide and its incidence is increasing in Australia. Transarterial therapy, predominantly transarterial chemoembolization (TACE) but increasingly transarterial radioembolization (TARE), plays an important role in patients with intermediate‐stage disease and preserved liver ...
Jonathan Tibballs, Warren Clements
wiley   +1 more source

Yttrium‐90 Radioembolization for the Treatment of Solitary, Unresectable HCC: The LEGACY Study

Hepatology, Volume 74, Issue 5, Page 2342-2352, November 2021., 2021
Background and Aims Locoregional therapies, including yttrium‐90 radioembolization, play an important role in the treatment of unresectable HCC. The aim of the LEGACY (Local radioEmbolization using Glass Microspheres for the Assessment of Tumor Control with Y‐90) study was to evaluate objective response rate (ORR) and duration of response (DoR) in ...
Riad Salem, Guy E. Johnson, Edward Kim, Ahsun Riaz, Vivian Bishay, Eveline Boucher, Kirk Fowers, Robert Lewandowski, Siddharth A. Padia   +8 more
wiley   +1 more source

Predictors of Successful Yttrium‐90 Radioembolization Bridging or Downstaging in Patients with Hepatocellular Carcinoma

Canadian Journal of Gastroenterology and Hepatology, Volume 2021, Issue 1, 2021., 2021
Purpose. This study aims to identify clinical and imaging prognosticators associated with the successful bridging or downstaging to liver transplantation (LT) in patients undergoing Yttrium‐90 radioembolization (Y90‐RE) for hepatocellular carcinoma (HCC). Methods.
Alexander Villalobos, William Wagstaff, Mian Guo, James Zhang, Zachary Bercu, Morgan J. Whitmore, Mircea M Cristescu, Bill S. Majdalany, Joel Wedd, Mehmet Akce, Joseph Magliocca, Marty T. Sellers, Nima Kokabi, Alessandro Granito   +13 more
wiley   +1 more source

Methods for selecting the best evidence to inform a NICE technology appraisal on selective internal radiation therapies for hepatocellular carcinoma

Systematic Reviews, 2020
Background Systematic reviews of medical devices are particularly challenging as the quality of evidence tends to be more limited than evidence on pharmaceutical products.
Ros Wade, Sahar Sharif-Hurst, Melissa Harden, Matthew Walton, Lindsay Claxton, Robert Hodgson, Alison Eastwood   +6 more
doaj   +1 more source

Yttrium-90 radioembolization as a possible new treatment for brain cancer: proof of concept and safety analysis in a canine model

EJNMMI Research, 2020
Purpose To evaluate the safety, feasibility, and preliminary efficacy of yttrium-90 (90Y) radioembolization (RE) as a minimally invasive treatment in a canine model with presumed spontaneous brain cancers.
Alexander S. Pasciak, Sasicha Manupipatpong, Ferdinand K. Hui, Larry Gainsburg, Rebecca Krimins, M. Christine Zink, Cory F. Brayton, Meaghan Morris, Jaime Sage, Danielle R. Donahue, Matthew R. Dreher, Dara L. Kraitchman, Clifford R. Weiss   +12 more
doaj   +1 more source