Results 71 to 80 of about 4,710,863 (306)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Internet of Things (IoT) Arduino-Based Classroom Monitoring Utilizes Temperature Sensors And CO2 Sensors

IJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2022
Comfort room temperature is determined by indoor air quality, such as temperature and CO2 gas. This study aims to determine the comfort of a class by reviewing the number of students, CO2 gas, and temperature in an Arduino-based classroom using an ...
Tri Suratno, Edi Saputra, Zainil Abidin, Daniel Arsa, Norman Syarief   +4 more
doaj   +1 more source

Direct thermal conductance measurements on suspended monocrystalline nanostructures [PDF]

, 1997
We describe and demonstrate a new class of devices that enable direct thermal conductance measurements on monocrystalline nanostructures. These are possible through our newly developed techniques for three-dimensional, successive surface nanomachining of
Roukes, M. L., Tighe, T. S., Worlock, J. M.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Experimental Assessment of the Energy Performance of a Double-Skin Semi-Transparent PV Window in the Hot-Summer and Cold-Winter Zone of China

Energies, 2018
The energy performance of the semi-transparent PV (STPV) window was carried out in a hot-summer and cold-winter zone of China. Semi-transparent PV (STPV) windows generate electric, reduce the heating load and aim to utilize daylighting efficiently.
Wei Wang, Wei Zhang, Lingzhi Xie, Yupeng Wu, Hao Tian, Lin Zheng   +5 more
doaj   +1 more source

Thermal Effects [PDF]

Water Environment Research, 2018
This review focuses on the research literature published in 2017 relating to thermal effects in wastewater and solid waste treatment. This review is divided into the following sections: wastewater treatment, recovery of nitrogen and phosphorus, membrane technology, reduction and recovery of heavy metal, and treatment and disposal of solid waste.
Siqi, Wang, Junpei, Ye, Panyue, Zhang, Hongjie, Wang   +3 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Reversible Single-Crystal to Single-Crystal Thermal Phase Transformation of 3-(2-Bromo-4-(1-methylethyl)phenyl)-1,1-dimethyl urea

Crystals, 2017
3-(2-Bromo-4-(1-methylethyl)phenyl)-1,1-dimethylurea was synthesized and structurally characterized at 296 K, 200 K and 140 K. A reversible thermal phase transformation was observed at ~170–180 K. On cooling, the structure transforms from a monoclinic to
Benson M. Kariuki, Gamal A. El-Hiti
doaj   +1 more source

Controlling the thermal contact resistance of a carbon nanotube heat spreader

, 2010
The ability to tune the thermal resistance of carbon nanotube mechanical supports from insulating to conducting could permit the next generation of thermal management devices.
Baloch, Kamal H., Cumings, John, Voskanian, Norvik   +2 more
core   +1 more source