Results 91 to 100 of about 1,137,079 (315)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Parametric Analysis of Effective Tissue Thermal Conductivity, Thermal Wave Characteristic, and Pulsatile Blood Flow on Temperature Distribution during Thermal Therapy

, 2017
This study examines the coupled effects of pulsatile blood flow in a thermally significant blood vessel, the effective thermal conductivity of tumor tissue, and the thermal relaxation time in solid tissues on the temperature distributions during thermal ...
Shih, Tzu-Ching;Huang, Huang-Wen;Wei, Wei-Che;Horng, Tzyy-Leng
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Digital twins in AI-controlled navigation tasks for autonomous UAV swarm

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï
The article presents the concept and architecture of digital twins (DT) in the tasks of autonomous swarm navigation for unmanned aerial vehicles (UAVs) controlled by artificial intelligence.
Michael Zgurovsky, Nataliya Pankratova, Igor Golinko, Kostiantyn Grishyn   +3 more
doaj   +1 more source

Thermal transfer simulation regarding the rotational moulding of polyamide 11 [PDF]

, 2013
Simulation of thermal phenomena in rotational moulding is very important to follow the evolution of the temperature in various zones of this process. It was a question of modelling heat gradients developing in rota-tional moulding part.
TCHARKHTCHI, Abbas, BENZIANE, Mokhtar, HAFSAOUI, Said Lofti   +2 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

CFD Analysis of Thermal Performance Enhancement in Ribbed Microchannels Using Nanofluids

Entropie
A 2-D numerical investigation was carried out to study the nanofluid flow and heat transfer inside a horizontal ribbed micro-channel. The alumina oxide nanoparticles were suspended in water as based fluid at different volume fraction 0, 2 and 4 ...
Khadija Madani, Rejeb Ben Maad
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A kinetic analysis of thermal decomposition of polyaniline and its composites with rare earth oxides

, 2015
The decomposition kinetics of the pure polyaniline (PANI), PANI/CeO2 composites, and PANI/Dy2O3 composites were investigated using thermogravimetry (TG) technique under air atmosphere.
Tan, Zhicheng, Huang, Zihang, Wang, Shaoxu, Li, Yini, Zhang, Shihui   +4 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source