Results 71 to 80 of about 2,851,896 (291)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Measuring labor productivity dynamics in U.S. industrial and electric power sectors: a case study (2014–2023)

Frontiers in Energy Research
This study proposes a subsystem methodology for measuring labor productivity in the U.S. industrial and electric power sectors by leveraging public data available between 2014 and 2023.
Nahuel Guaita, Silvio Guaita, Mauricio Tano, Eliezer A. Reyes Molina   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Room-temperature FeSi2-doped Cu2Se thermoelectric films with enhanced figure of merit

Scientific Reports
Thermoelectric (TE) materials offer a promising pathway toward achieving carbon neutrality by converting waste heat into electricity. The enhancement of their figure-of-merit (zT) depends on optimizing the composition of materials and nanostructures ...
Masahiro Goto, Michiko Sasaki, Taku Moronaga, Toru Hara, Yibin Xu   +4 more
doaj   +1 more source

Microtwinning avalanches induced the Protevin–Le Châtelier effect in PWA1483 at 750 °C

Materials Research Letters
The flow behavior and deformation mechanisms of the [001]-oriented single-crystal nickel-based superalloy PWA1483 are investigated under quasi-static compressive and tensile loading conditions at 750°C.
Jiao Li, Peng Zhang, Jiaming Bai, Peng Liu, Yong Yuan, Xiaolong Song, Yuefeng Gu   +6 more
doaj   +1 more source

Superstring in a pp-wave background at finite temperature - TFD approach

, 2004
A thermodynamical analysis for the type IIB superstring in a pp-wave background is considered. The thermal Fock space is built and the temperature SUSY breaking appears naturally by analyzing the thermal vacuum.
A.L. Gadelha, Abdalla, Abdalla, Abdalla, Abdalla, Abdalla, Alvarez, Alvarez-Gaumé, Atick, Berenstein, Blau, Blau, Brower, Daniel L. Nedel, Das, Fujisaki, Fujisaki, Greene, Grignani, Leblanc, Leblanc, M.C.B. Abdalla, Maldacena, Matsumoto, Metsaev, Metsaev, Nakagawa, Ojima, Pando Zayas, Pankiewicz, Pankiewicz, Polchinski, Russo, Spradin, Spradin, Sugawara, Takahasi, Vancea, Witten   +38 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Non-linear fire-resistance analysis of reinforced concrete beams [PDF]

, 2003
The non-linear structural analysis of reinforced concrete beams in fire consists of three separate steps: (i) The estimation of the rise of surrounding air temperature due to fire; (ii) the determination of the distribution of the temperature within the ...
Bratina, Sebastjan, Planinc, Igor, Saje, Miran, Turk, Goran   +3 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source