Results 71 to 80 of about 1,137,079 (315)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Room-temperature FeSi2-doped Cu2Se thermoelectric films with enhanced figure of merit

Scientific Reports
Thermoelectric (TE) materials offer a promising pathway toward achieving carbon neutrality by converting waste heat into electricity. The enhancement of their figure-of-merit (zT) depends on optimizing the composition of materials and nanostructures ...
Masahiro Goto, Michiko Sasaki, Taku Moronaga, Toru Hara, Yibin Xu   +4 more
doaj   +1 more source

Microtwinning avalanches induced the Protevin–Le Châtelier effect in PWA1483 at 750 °C

Materials Research Letters
The flow behavior and deformation mechanisms of the [001]-oriented single-crystal nickel-based superalloy PWA1483 are investigated under quasi-static compressive and tensile loading conditions at 750°C.
Jiao Li, Peng Zhang, Jiaming Bai, Peng Liu, Yong Yuan, Xiaolong Song, Yuefeng Gu   +6 more
doaj   +1 more source

Thermal study of chalcones

, 2018
Chalcones α-β-unsaturated ketones are found in large plant species. Synthesis of chalcones and its three analogues hydroxy group at 2′, 3′ and 4′ positions (2–4) was carried out.
Leonardo Miziara Barboza Ferreira, Ribeiro, Clóvis Augusto, Kobelnik, Marcelo, Ferreira, Leonardo Miziara Barboza, Dutra, Luiz Antonio, Dutra, Luiz Antonio [UNESP], Ferreira, Leonardo Miziara Barboza [UNESP], Regasini, Luis Octavio, Clóvis Augusto Ribeiro, Luiz Antonio Dutra, Luis Octavio Regasini, da Silva Bolzani, Vanderlan [UNESP], Vanderlan da Silva Bolzani, Marcelo Kobelnik, da Silva Bolzani, Vanderlan, Regasini, Luis Octavio [UNESP], Ribeiro, Clóvis Augusto [UNESP]   +16 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Sewage sludge coke estimation using thermal analysis

, 2011
The imposition of more stringent legislation by CETESB in the State of So Paulo (Brazil) governing the disposal and utilization of sewage sludge, coupled with the growth in its generation has prompted a drive for alternative uses of sewage sludge.
de Morais, Leandro Cardoso [UNESP], de Morais, Leandro Cardoso, Buchler, Pedro Mauricio, Jo Dweck, Dweck, Jo, Leandro Cardoso de Morais, Viana, Marcelo Mendes [UNESP], Pedro Maurício Buchler, Maltez Melchert, Maura Berger, Maltez Melchert, Maura Berger [UNESP], Buchler, Pedro Mauricio [UNESP], Marcelo Mendes Viana, Viana, Marcelo Mendes, Maura Berger Maltez Melchert   +13 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Thermal decomposition of metatorbernite - A controlled rate thermal analysis study

, 2005
The mineral metatorbernite, Cu[(UO2)2(PO4)]2•8H2O, has been studied using a combination of energy dispersive X-ray analysis, X-ray diffraction, dynamic and controlled rate thermal analysis techniques. X-ray diffraction shows that the starting material in
Weier, Matt L., Martens, Wayde N., Kristof, Janos, Horvath, Erzsebet, Frost, Ray L.   +4 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Thermal behavior of a concrete recycling unit during the transition from diesel-fired to electric hot air generator

Case Studies in Thermal Engineering
For the advancement of sustainable and cleaner operation in concrete recycling, the Heating Air Classification System (HAS) requires replacing the existing diesel-fired burner with an electric heating technology. This study contributes to that transition
Nishab Ali, Osama Zaid, Abraham Teklay Gebremariam, Arun Chand, Andallib Tariq   +4 more
doaj   +1 more source