Results 81 to 90 of about 25,353,476 (264)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Measurements of ionic liquids thermal conductivity and thermal diffusivity [PDF]

open access: yes, 2016
Thermal conductivity and thermal diffusivity of ionic liquids (ILs) are investigated in this work. A hot disk method for ILs thermal conductivity and thermal diffusivity measurement is utilized.
Yansong Zhao   +7 more
core   +1 more source

Thermal behavior of a concrete recycling unit during the transition from diesel-fired to electric hot air generator

open access: yesCase Studies in Thermal Engineering
For the advancement of sustainable and cleaner operation in concrete recycling, the Heating Air Classification System (HAS) requires replacing the existing diesel-fired burner with an electric heating technology. This study contributes to that transition
Nishab Ali   +4 more
doaj   +1 more source

Low-cost carbonized kelp for highly efficient solar steam generation

open access: yesAIP Advances, 2019
Using abundant solar energy to generate steam offers unique solution overcoming the lack of freshwater resources. Despite extensive explorations, low-cost devices with high efficiency are still critically wanting.
Yawen Lin   +5 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Finite element analysis of thermal fatigue in thermal barrier coatings (TBC)

open access: yes, 2009
A Finite element model of plasma sprayed TBC’s was developed to estimate the stress induced by thermal cycling experiments. A heat transfer analysis was performed to evaluate the temperature distribution on the specimen during the cooling under an ...
Lavacchi, Alessandro   +4 more
core  

Controlled Rate Thermal analysis of hydromagnesite [PDF]

open access: yes, 2008
The reaction of magnesium minerals such as brucite with CO2 is important in the sequestration of CO2. The study of the thermal stability of hydromagnesite and diagenetically related compounds is of fundamental importance to this sequestration.
Locke, Ashley J.   +11 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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