Results 51 to 60 of about 1,137,079 (315)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Cure kinetics of liquid crystalline epoxy resins based on biphenyl mesogen

, 2014
The cure kinetics of a biphenyl-based liquid crystalline (LC) epoxy resin (LCER) was studied using differential scanning calorimetry (DSC) and polarized optical microscopy. The effects of LC phase formation on the cure kinetics were investigated.
Kessler, Michael, Li, Yuzhan
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The use of thermal analysis methods for monitoring the development of bitumen reservoirs using thermal recovery technologies [PDF]

, 2017
© 2017 Akadémiai Kiadó, Budapest, Hungary The products obtained from production wells of Ashalchinsk and Mordovo-Karmalsk bitumen fields of the Republic of Tatarstan (Russia) using thermal recovery technologies as well as the core materials recovered ...
Ganeeva Y., Romanov G., Okhotnikova E., Yusupova T.   +3 more
core  

Thermal analysis of prednicarbate and characterization of thermal decomposition product

, 2010
In the present work, the thermal behavior of prednicarbate was studied using DSC and TG/DTG. The solid product remaining at the first decomposition step of the drug was isolated by TG, in air and N(2) atmospheres and was characterized using LC-MS/MS, NMR,
CARVALHO, Flavio Machado de Sousa, BARROS, Fabio Alessandro Proenca, MATOS, Jivaldo Rosario, SALVIO NETO, Helio   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Batch Sintering of FeO·OH and Fe₂O₃ Blends: Chemical and Metallurgical Characterization

Metals
A sample of goethite iron ore sinter feed (G_SF) was employed as a raw material in a sintering bed. This sample partially replaced hematite sinter feed (H_SF), which is currently used as raw material in a sintering plant in the state of Minas Gerais ...
Igor J. U. V. Pereira, Henrique C. S. Coelho, Cláudio G. Santos, Eduardo A. Brocchi, Rodrigo F. M. Souza, Victor A. A. Oliveira   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Thermal analysis of high explosives: liquid state decomposition of RDX [PDF]

, 2000
journal articleNonisothermal thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) have been applied to the thermal decomposition of RDX.
Wight, Charles Albert, Long, G. T.; Vyazovkin, S.; Brems, B. A.   +1 more
core  

Measurements of ionic liquids thermal conductivity and thermal diffusivity [PDF]

, 2016
Thermal conductivity and thermal diffusivity of ionic liquids (ILs) are investigated in this work. A hot disk method for ILs thermal conductivity and thermal diffusivity measurement is utilized.
Yansong Zhao, Yingpeng Zhen, Zhao, Yansong, Boström, Tobias, Tobias Boström, Zhen, Yingpeng, Jelle, Bjørn Petter, Bjørn Petter Jelle   +7 more
core   +1 more source