Results 81 to 90 of about 536,814 (315)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Optimization of compact fuzzy controllers used for temperature regulation

Visión Electrónica, 2020
This document shows the optimization of different configurations of a compact fuzzy controller for temperature regulation in a room; such configurations are established considering the analogy with different discrete linear controllers; the model is ...
Helbert Eduardo Espitia Cuchango, Iván Machón-González, Hilario López-García   +2 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Investigation of the thermal regime of microsatellite optoelectronic telescopic complex under operating conditions

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2017
An optoelectronic telescopic lens-type complex is proposed for the purpose of creating a domestic constellation of Earth remote sensing satellites with the ability of timely obtaining of the imagery on-demand.
S. V. Tsaplin, S. A. Bolychev
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Operational Engineering of the COLUMBUS Thermal and Environmental Control System: Achievements, Optimizations

, 2010
After commissioning of the European space-borne science laboratory Columbus, many operational products had to be improved and adapted to changing environmental conditions and new operational experiences.
Porth, N., Kohlhase, A. O., Doye, J.
core  

Numerical investigation of heat transfer mechanism in an embedded PCM-TEG for better overall performance under the fluctuating heat source

Case Studies in Thermal Engineering
Using phase change materials (PCM) can effectively ensure the stable operation of semiconductor thermoelectric generators (TEGs). Conventional PCM-TEG structures exhibit relatively poor output performance due to energy barriers caused by low thermal ...
Jing-Hui Meng, Xing-Hao Zhu, Yan Liu, Min Yang, Gui Lu   +4 more
doaj   +1 more source

Possibilities of Thermal Systems Control

Transactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2009
This contribution describes different approaches to thermal system control. Not only PID control but also sliding mode controls were used. In addition the different modifications of sliding mode control were used, such as extension with integral element or continuous substitution of sign function.
Renata WAGNEROVÁ, Lukáš RICHTR
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Loop heat pipe for thermal conditions supplying systems for elements of radio electronic equipment [PDF]

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2010
The loop heat pipe design presented in the article provides the transmission of thermal flow up to 105 W when working in temperature range of 20—90°C and on any space orientation.
Khayrnasov S. М.
doaj