Results 71 to 80 of about 536,814 (315)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Power system real-time thermal rating estimation [PDF]

, 2010
This Thesis describes the development and testing of a real-time rating estimation algorithm developed at Durham University within the framework of the partially Government-funded research and development project “Active network management based on ...
MICHIORRI, ANDREA
core  

Holistic thermal management strategies for electric vehicles

, 2022
S.67-80Thermal management systems in vehicles ensure the demand-based supply and extraction of the heating and cooling energy that is needed to fulfil the specific requirements of components regarding their operating temperatures and to guarantee thermal
Hütter, M., Kuitunen, S., König, W.
core   +1 more source

Experimental Study on Vacuum Thermal Performance of RTPV

Yuanzineng kexue jishu, 2023
In the 250 Wt RTPV (radioisotope thermophoto-voltaic) system, the heat source operates at a temperature above 1 000 ℃, which requires a long term stable thermal insulation devices. In this paper, three types of non-sealed high temperature MLI (multilayer
SU Sheng;SHAO Jianxiong;QIU Jiawen;CHEN Yang;MA Juyin;TIAN Dai;MA Bin;HAN Chengzhi
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Adaptive Variable Universe Fuzzy Droop Control Based on a Novel Multi-Strategy Harris Hawk Optimization Algorithm for a Direct Current Microgrid with Hybrid Energy Storage

Energies
In the off-grid photovoltaic DC microgrid, traditional droop control encounters challenges in effectively adjusting the droop coefficient in response to varying power fluctuation frequencies, which can be influenced by factors such as line impedance ...
Chen Wang, Shangbin Jiao, Youmin Zhang, Xiaohui Wang, Yujun Li   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A fuzzy approach to building thermal systems optimization. [PDF]

, 1999
Optimization of building thermal systems is treated in the paper in the framework of fuzzy mathematical programming. This new approach allows to formulate more precisely the problem which compromises energy saving and thermal comfort satisfaction under ...
Angelov, Plamen, Plamen Angelov
core  

Thermal control design for an automated fiber placement machine

Science and Engineering of Composite Materials, 2014
One of the important concerns about the quality of the thermoplastic composite in automated fiber placement (AFP) process is the degradation of thermoplastic resin, resulting from the overheating or the lack of proper heating by the heating system used ...
Hajiloo Amir, Xie Wenfang, Hoa Suong V., Khan Salman   +3 more
doaj   +1 more source