Results 51 to 60 of about 536,814 (315)

Investigation of thermal conditions of nanosatellite optoelectronic telescopic module for different modes of operation

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2019
The problem of studying thermal conditions of the optoelectronic telescopic module of a nanosatellite under the influence of operating conditions is considered. To maintain optimal thermal conditions of the telescopic lens, a thermal control system based
S. V. Tsaplin, S. A. Bolychev
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Thermal design of «AIST» small spacecraft

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2016
Thermal design is a prerequisite essential to design a satellite. In space environment, it makes it possible for the satellite to survive in extreme hot and cold conditions.
D. S. Kulikov, Ja. N. Erilkin
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Multi phase system for metal disc induction heating: modelling and RMS current control [PDF]

, 2012
This paper presents a multi phase induction system modelling for a metal disc heating and further industrial applications such as hot strip mill. An original architecture, with three concentric inductors supplied by three resonant current inverters leads
Pateau, Olivier, Caux, Stéphane, Maussion, Pascal, Egalon, Julie, Souley, Majid   +4 more
core   +1 more source

Nondestructive 3D Imaging of Microscale Damage inside Polymers—Based on the Discovery of Self‐Excited Fluorescence Effect Induced by Electrical Field

Advanced Science, 2023
The development of high‐precision, non‐destructive, and three‐dimensional (3D) in situ imaging of micro‐scale damage inside polymers is extremely challenging.
Wenxia Sima, Xinyu Tang, Potao Sun, Zhenkun Sun, Tao Yuan, Ming Yang, Chun Zhu, Zeyan Shi, Qin Deng   +8 more
doaj   +1 more source

Short-term photovoltaic power forecasting method based on convolutional neural network

Energy Reports, 2022
This research proposes a hybrid model that combines the convolutional neural network (CNN) and the bidirectional long short-term memory network (BiLSTM) to accurately estimate the energy output of a short-term photovoltaic system.
Yutong He, Qingzhong Gao, Yuanyuan Jin, Fang Liu   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Flexible Electric Power Control for Coal-Fired Units by Incorporating Feedwater Bypass

IEEE Access, 2019
The improvement of the operating flexibility of a thermal power unit has always been an essential issue due to its substantial support to power system stability. In addition, this issue has become increasingly important for the large-scale integration of
Wei Wang, Jizhen Liu, Deliang Zeng, Yuguang Niu, Li Sun   +4 more
doaj   +1 more source