Results 71 to 80 of about 6,411,821 (351)

The Bree problem with different yield stresses on-load and off-load and application to creep ratcheting

, 2014
The ratchet boundaries and ratchet strains are derived for the Bree problem and an elastic perfectly plastic material with different yield stresses on-load and off-load.
Chen, Haofeng, Ure, James, Bradford, R.A.W.   +2 more
core   +1 more source

Microstructures and Thermal Cycling Properties of Thermal Barrier Coatings Deposited by Hybrid Water-Stabilized Plasma Torch

, 2020
Hybrid water-stabilized plasma (WSP-H) torches provide high-enthalpy plasma which may be utilized for high-throughput and yet economical spraying of coatings from powders, suspensions, and solutions.
Tesar, Tomas,, Gupta, Mohit Kumar,, Medricky, Jan,, Musalek, Radek,, Lukac, Frantisek,, Chraska, Tomas,   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Corrosion behaviour of thermal cycled aluminium hybrid composites reinforced with rice husk ash and silicon carbide

Journal of King Saud University: Engineering Sciences, 2018
The corrosion behaviour of aluminium hybrid composites reinforced with rice husk ash and silicon carbide subjected to thermal cycling has been investigated.
Kenneth Kanayo Alaneme, Joshua Ogheneakporobo Ekperusi, Samuel Ranti Oke   +2 more
doaj   +1 more source

Thermal cycling creep properties of a directionally solidified superalloy DZ125

, 2022
Aero-engine turbine blades may suffer overheating during service, which can result in severe microstructural and mechanical degradation within tens of seconds.
Antonov, Stoichko, Feng, Qiang, Cormier, Jonathan, Utada, S., Guo, Xiaotong, An, Wenrui, Zheng, W., Cormier, J., Antonov, S., An, W., Feng, Q., Guo, X., Zheng, Weiwei, Utada, Satoshi   +13 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Thermal-Resistance-Based Reliability of TIM1 Materials in a Lidded Thermal Test Vehicle Under Active Thermal Load-Cycling

The reliability of thermal interface materials (TIM1) in lidded high-power flip-chip packages is investigated using a thermal test vehicle (TTV) under active power cycling.
Sternberg, Maik, Abo Ras, Mohamad, Wargulski, Dan Ralf, May, Daniel, Pareek, Kaushal Arun, Wunderle, Bernhard   +5 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Thermal Changes in the Normal Menstrual Cycle [PDF]

BMJ, 1963
This study was undertaken in order to establish what changes of temperature occurred during the normal menstrual cycle of 115 fertile women. Temperature charts of 1134 cycles were provided by the patients. Out of this number 1088 cycles showed the rise in temperature which is associated with ovulation. Although there was a wide variation in time the
openaire   +2 more sources