Results 51 to 60 of about 1,369,127 (302)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Experimental performance of water cooled building integrated photovoltaic/thermal solar collectors [PDF]

, 2008
The idea of integrating water cooled photovoltaic/thermal collectors into building structures (BIPVT collectors) to provide electrical and heat energy is an area that has received only limited attention.
Anderson, Timothy Nicholas, Carson, James K., Duke, Mike   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Bi-LSTM, GRU and 1D-CNN models for short-term photovoltaic panel efficiency forecasting case amorphous silicon grid-connected PV system

Results in Engineering
Photovoltaic (PV) panels stand as a prominent solution to meet the world's growing energy demands, due to their resistance to hard climate conditions, low-cost maintenance, and long lifetime. Nonetheless, the integration of PV power into electrical grids
Abdellatif Ait Mansour, Amine Tilioua, Mohammed Touzani   +2 more
doaj   +1 more source

Thermoelectric generator at optimal power with external and internal irreversibilities

, 2018
There are few exact results on optimal power conditions for a thermoelectric generator in the presence of both external and internal irreversibilities---modelled as non-ideal thermal contacts and Joule heating, respectively.
Johal, Ramandeep S., Kaur, Jasleen
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Energy Demand Response in a Food-Processing Plant: A Deep Reinforcement Learning Approach

Energies
The food industry faces significant challenges in managing operational costs due to its high energy intensity and rising energy prices. Industrial food-processing facilities, with substantial thermal capacities and large demands for cooling and heating ...
Philipp Wohlgenannt, Sebastian Hegenbart, Elias Eder, Mohan Kolhe, Peter Kepplinger   +4 more
doaj   +1 more source

Investigation of the thermal efficiencies of a solar dryer

Energy Conversion and Management, 1995
Abstract This paper deals with the construction and performance of a solar powered drying system consisting of a solar air heater and a drying chamber. The thermal efficiencies of both the solar air heater and the drying section as a function of typical physical parameters and the experimental results for different food products at different air flow
TIRIS, C, TIRIS, M, DINCER, I
openaire   +2 more sources

DISCUSSION. THE THERMAL EFFICIENCY OF STEAM ENGINES. [PDF]

Minutes of the Proceedings of the Institution of Civil Engineers, 1896
n ...
Baker, Sir B., Davey, H., Donkin, B., Carter, E. T., Sankey, H. R., Beaumont, W., Rumley, J. G. M., Schonheyder, W.   +7 more
openaire   +1 more source