Results 71 to 80 of about 1,369,127 (302)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Machine learning-based predictive model for thermal comfort and energy optimization in smart buildings

Results in Engineering
In the current context of energy transition and increasing climate change, optimizing building performance has become a critical objective. Efficient energy use and occupant comfort are paramount considerations in building design and operation.
Youssef Boutahri, Amine Tilioua
doaj   +1 more source

Integration of Phase Change Material in the Design of Solar Concentrator-Based Water Heating System

Entropy, 2021
Indonesia has been blessed with excellent solar heat distribution, which can be used as renewable energy to heat water. Various technologies have been developed to utilize these inexhaustible thermodynamic resources, in the form of photons arrays ...
Teuku Azuar Rizal, Muhammad Amin, Syamsul Bahri Widodo, Nazaruddin Abdul Rachman, Fazri Amir, Nurhalim Pane, Teuku Meurah Indra Mahlia   +6 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Energy Management Simulation in a PEM Fuel Cell System [PDF]

Hydrogen, Fuel Cell & Energy Storage, 2015
In this research the simulation of an air independent Proton Exchange Membrane Fuel Cell (PEMFC) propulsion system was taken into consideration. The system consists of several parts including PEM fuel cell stack, metal hydride and liquid oxygen (LOX ...
Mohammad Alijanpour, Majid Shateri, Mojtaba Aghajani Delavar, Mousa Farhadi   +3 more
doaj   +1 more source

Detection of a Thermal Spectral Component in the Prompt Emission of GRB 100724B [PDF]

, 2010
Observations of GRB 100724B with the Fermi Gamma-Ray Burst Monitor (GBM) find that the spectrum is dominated by the typical Band functional form, which is usually taken to represent a non-thermal emission component, but also includes a statistically ...
Bhat, P. N., Bissaldi, Elisabetta, Briggs, Michael S., Burgess, Michael, Camero-Arranz, Ascensión, Chaplin, Vandiver, Connaughton, Valerie, Daigne, Frédéric, Diehl, Roland, Fishman, Gerald, Foley, Suzanne, Gibby, Melissa, Giles, Misty M., Goldstein, Adam, Greiner, Jochen, Gruber, David, Guiriec, Sylvain, Kippen, Marc, Kouveliotou, Chryssa, McBreen, Sheila, McEnery, Julie, Meegan, Charles A., Mészáros, Peter, Omodei, Nicola, Paciesas, William, Preece, Robert, Rau, Arne, Ryde, Felix, Tierney, Dave, van der Horst, Alexander J., von Kienlin, Andreas, Wilson-Hodge, Colleen   +31 more
core   +4 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Automatic thermal switch Patent [PDF]

, 1966
Automatic thermal switch for improving efficiency of cooling gases below 40
Wiebe, E. R.
core   +1 more source

Quantum Thermal Machine as a Thermometer

, 2017
We propose the use of a quantum thermal machine for low-temperature thermometry. A hot thermal reservoir coupled to the machine allows for simultaneously cooling the sample while determining its temperature without knowing the model-dependent coupling ...
Brask, Jonatan Bohr, Brunner, Nicolas, Hofer, Patrick P., Perarnau-Llobet, Martí   +3 more
core   +1 more source

Fine Structures of Shock of SN 1006 with the Chandra Observation [PDF]

, 2003
The north east shell of SN 1006 is the most probable acceleration site of high energy electrons (up to ~ 100 TeV) with the Fermi acceleration mechanism at the shock front.
Aharonian F. A., Aya Bamba, Bamba A., Bell A. R., Dyer K. K., Hess V. F., Jones F. C., Katsuji Koyama, Koyama K., Masaru Ueno, Muraishi H., Ryo Yamazaki, Skilling J., Vink J.   +13 more
core   +3 more sources