Results 61 to 70 of about 382,457 (261)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Advanced materials and fabricating approaches for proton exchange membrane fuel cells

Responsive Materials
Production of electrical energy in an environmental‐friendly manner is important for meeting the increasing demand of electricity in smart vehicles and energy devices.
Xiangru Kong, Tao Zhou, Long Wang, Kuaile Liu, Xiaozhong Huang, Tao Li, Zhu Sun, Feng Gong, Weiwei Fan, Rui Xiao   +9 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Reconstruction of 3D Temperature Profile of Radiative Participatory Flame Based on Digital Refocusing Technique of Light Field Camera

International Journal of Photoenergy, 2019
Accurate and reliable measurements of the 3D flame temperature profile are highly desirable to achieve in-depth understanding of the combustion and pollutant formation processes.
Biao Zhang, Chen Wang, Yudong Liu, Chuanlong Xu, Qi Qi   +4 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Combined Model for IAQ Assessment: Part 1—Morphology of the Model and Selection of Substantial Air Quality Impact Sub-Models

Applied Sciences, 2019
Indoor air quality (IAQ) is one of the most important elements affecting a building user’s comfort and satisfaction. Currently, many methods of assessing the quality of indoor air have been described in the literature. In the authors’ opinion,
Michał Piasecki, Krystyna Barbara Kostyrko   +1 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Design, synthesis, and progress of covalent organic frameworks (COFs)-based electrocatalysts for valorisation of biomass-derived platform chemicals

Materials Today Advances
The heavy reliance on fossil-based industries for basic chemicals not only contributes to severe global environmental problems but also hampers the sustainable development of the whole society. In addressing this issue, electrocatalysis utilizing biomass-
Changyu Weng, Hongmei Yuan, Lungang Chen, Xinghua Zhang, Qi Zhang, Longlong Ma, Jianguo Liu   +6 more
doaj   +1 more source