Results 61 to 70 of about 479,187 (312)

Coarse-grained model and force field development for predicting phase change and thermal transport in polyethylene

Cailiao gongcheng, 2020
Coarse-grained model and force field for predicting phase change and thermal transport in meso-scale polyethylene were developed and its accuracy was validated.
CAI Zhuang-li, ZHAO Ling-ling, YU Xi-fan, CHEN Chao   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Effect of Flue Gas Composition on Mercury Removal by Injecting Rice Husk-Derived Activated Carbon

Zhongguo dianli, 2019
The flue gas mercury removal experiment was carried out on a 0.3MW pilot scale circulating fluidized bed test facility by injecting biomass based activated carbon which is originally derived from rice husk and then modified by halogenated ammonium ...
Jun TAO, Xiaobing GU, Tianfang HUANG, Shuai LIU, Peng HU, Lu DONG, Yaji HUANG, Yufeng DUAN   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Constructing high-performance micro fuel electrodes for reversible proton ceramic electrochemical cells

Electrochemistry Communications
Reversible proton ceramic electrochemical cells (R-PCECs) are of great interest as efficient energy conversion device. Optimization of structural design can enhance the mechanical properties and gas transport of the cells, resulting in improved ...
Yeqing Ling, Feifan Huang, Bin Wang, Tao Li   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

CFD model of thermal and velocity conditions in a particular indoor environment [PDF]

, 2013
The demand for maintaining high indoor environmental quality (IEQ) with the minimum energy consumption is rapidly increasing. In the recent years, several studies have been completed to investigate the impact of indoor environment factors on human ...
Mora Pérez, Miguel, López Jiménez, Petra Amparo, Guillén Guillamón, Ignacio Enrique, López-Patiño, Gonzalo   +3 more
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Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Field Studies of Subjective Effects on Thermal Comfort in a University Classroom [PDF]

, 2006
Two field studies were conducted in a university classroom in the autumn of 2004 in Harbin. The objective of these studies was to assess the thermal conditions and the subjective effects on occupant thermal comfort. A field study was carried out when the
Wang, J., Wang, Z.
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