Results 51 to 60 of about 1,074,745 (290)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A particle swarm optimisation-based Grey prediction model for thermal error compensation on CNC machine tools [PDF]
, 2015 Thermal errors can have a significant effect on CNC machine tool accuracy. The thermal error compensation system has become a cost-effective method of improving machine tool accuracy in recent years.
Abdulshahed, Ali +2 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Ab initio based thermal property predictions at a low cost : an error analysis [PDF]
, 2014 Ab initio calculations often do not straightforwardly yield the thermal properties of a material yet. It requires considerable computational efforts, for example, to predict the volumetric thermal expansion coefficient alpha(V) or the melting temperature
Cottenier, Stefaan +3 more
core +1 more source
Error compensation for thermally induced errors on a machine tool [PDF]
, 1996 Heat flow from internal and external sources and the environment create machine deformations, resulting in positioning errors between the tool and workpiece. There is no industrially accepted method for thermal error compensation. A simple model has been selected that linearly relates discrete temperature measurements to the deflection.
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Measurements of Temperature of CNC Machine Tool Ball Screw Utilising IR Method
International Journal of Applied Mechanics and Engineering, 2017 In numerous papers it is proposed to use IR measurements of feed axis ball screw temperature distribution in order to compensate CNC machine tool thermal errors.
J. Zapłata
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Thermal error prediction and optimal design of cooling structure for oscillating head housing
Case Studies in Thermal EngineeringThe thermal error of machine tool has always been an important reason affecting the accuracy of machine tool. In modern methods to reduce thermal error, thermal error compensation method and thermal error isolation method are two methods with high ...
Zhaolong Li +6 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source