Results 51 to 60 of about 10,460,767 (272)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Application of GNNMCI(1, N) to environmental thermal error modelling of CNC machine tools [PDF]
, 2013 Thermal errors are often quoted as being the largest contributor to inaccuracy of CNC machine tools, but they can be effectively reduced using error compensation.
Longstaff, Andrew P. +3 more
core +2 more sources
Italian National Conference on SensorsAiming at the shortcomings of single-sensor sensing information characterization ability, which is easily interfered with by external environmental factors, a method of intelligent perception is proposed in this paper. This method integrates multi-source
Ze-Qing Yang +7 more
semanticscholar +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Error analysis of the thermal cell for soil thermal conductivity measurement [PDF]
Proceedings of the Institution of Civil Engineers - Geotechnical Engineering, 2017 Soil thermal conductivity is an important factor in the design of energy foundations and other ground heat exchanger systems. Laboratory tests in a thermal cell are often used to determine the thermal conductivity of soil specimens. Two interpretation methods have been suggested.
Low, JE, Loveridge, FA, Powrie, W
openaire +3 more sources
Digital Twin for Volumetric Thermal Error Compensation of Large Machine Tools
Italian National Conference on SensorsMachine tool accuracy is greatly influenced by geometric and thermal errors that cause positioning deviations within its working volume. Conventionally, these two error sources are treated separately, with distinct procedures employed for their ...
B. Iñigo +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Eksploatacja i Niezawodnosc - Maintenance and Reliability, 2022 Machining accuracy reliability as a key index of CNC machine tools is seriously influenced by the geometric and thermal errors. In the paper, a spindle unit thermal error modeling and machining accuracy reliability analysis method is proposed.
Ziling Zhang +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
A Novel Hybrid Neural Network with Optimized Feature Selection for Spindle Thermal Error Prediction
Applied System InnovationIn modern intelligent manufacturing, spindle thermal errors are critical to machining accuracy. To address this, we propose a two-stage prediction framework.
Lifeng Yin +5 more
doaj +1 more source