Results 91 to 100 of about 4,483,704 (311)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The evolution and population diversity of human-specific segmental duplications [PDF]

, 2017
Segmental duplications contribute to human evolution, adaptation and genomic instability but are often poorly characterized. We investigate the evolution, genetic variation and coding potential of human-specific segmental duplications (HSDs). We identify
Nuttle, Xander, Wilson, Richard K, Nelson, Bradley J, Xander Nuttle, Laura Denman, Nelson, Bradley J., Kenneth Mark, Kelsi Penewit, Huddleston, John, Malig, Maika, Cantsilieris, Stuart, Tina A. Lindsay-Graves, Harshman, Lana, John Huddleston, Penn, Osnat, Stessman, Holly A, Stessman, Holly A. F., Wilson, Richard K., Dennis, Megan Y, Espinoza, Claudia, Dennis, Megan Y., Penewit, Kelsi, Francesca Antonacci, Janke, Nicolette, Stuart Cantsilieris, Baker, Carl, Richard K. Wilson, Holly A. F. Stessman, Carl Baker, Lindsay-Graves, Tina A, Bradley J. Nelson, Maika Malig, Evan E. Eichler, Graves, Tina A, Stessman, Holly AF, Megan Y. Dennis, Archana Raja, Lana Harshman, Eichler, Evan E, Hoekzema, Kendra, Nicolette Janke, Lindsay-graves, Tina A., Claudia Espinoza, Mark, Kenneth, Denman, Laura, Eichler, Evan E., Antonacci, Francesca, Raja, Archana, Osnat Penn, Kendra Hoekzema   +49 more
core   +1 more source

Variations of Heat Flux and Elastic Thickness of Mercury From 3‐D Thermal Evolution Modeling

Geophysical Research Letters
Mercury's low obliquity and 3:2 spin‐orbit resonance create a surface temperature distribution with large latitudinal and longitudinal variations. These propagate via thermal conduction through the thin silicate shell influencing the interior temperature
Aymeric Fleury, Ana‐Catalina Plesa, Nicola Tosi, Michaela Walterová, Doris Breuer   +4 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Thermal transfer simulation regarding the rotational moulding of polyamide 11 [PDF]

, 2013
Simulation of thermal phenomena in rotational moulding is very important to follow the evolution of the temperature in various zones of this process. It was a question of modelling heat gradients developing in rota-tional moulding part.
TCHARKHTCHI, Abbas, BENZIANE, Mokhtar, HAFSAOUI, Said Lofti   +2 more
core   +1 more source

Rifting and thermal evolution of the Northwestern Mediterranean

Annals of Geophysics, 1995
The structural setting of the Northwestern Mediterranean stems from tectonothermal processes which reflect on the nature of the crust. The Oligocene to Present evolution is here analysed with a thermal model which takes into account the significant extension of the continentallithosphere before the onset of sea-floor spread- ing in the bathyal zone ...
PASQUALE, VINCENZO, VERDOYA, MASSIMO, CHIOZZI P.   +2 more
openaire   +5 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Toward a solid-state thermal diode for room-temperature magnetocaloric energy conversion [PDF]

, 2020
Thermal control elements, i.e., thermal diodes, switches, and regulators, can control the heat flow in an analogous way in how electronic devices control electrical currents.
Andrej Kitanovski, Kutnjak, Zdravko, Klinar, Katja, Muñoz Rojo, Miguel, Katja Klinar, Kitanovski, Andrej, Zdravko Kutnjak, Miguel Muñoz Rojo   +7 more
core   +2 more sources

Tectonic-structural systems of Mars: Is it possible to use them to reconstruct its thermal evolution? [PDF]

Geofísica Internacional, 2004
This work tries to establish the possible relationship among cortical stresses evidenced by faults mapped in the surface and thermal evolution on Mars.
J. F. Valdés-Galicia, Antonio H. Barosio   +1 more
doaj  

Residual stress evolution regularity in thermal barrier coatings under thermal shock loading

Theoretical and Applied Mechanics Letters, 2014
Residual stress evolution regularity in thermal barrier ceramic coatings (TBCs) under different cycles of thermal shock loading of 1100°C was investigated by the microscopic digital image correlation (DIC) and micro-Raman spectroscopy, respectively.
Ximin Chen, Zhanwei Liu, Yang Yang
doaj   +1 more source