Results 71 to 80 of about 1,078,179 (287)

Process and Controlling Factors of Pore Evolution in Marine-Continental Transitional Black Shale—An Example From Permian Shanxi Formation in the Eastern Margin of Ordos Basin

open access: yesFrontiers in Earth Science, 2022
Pore and pore network evolution of shale is critical for the evaluation the pore system in shale gas reservoirs. Thermal maturation effect acts as an indispensable role in porosity evolution.
Jin Wu   +10 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Thermal Evolution of a Pulsating Neutron Star

open access: yes, 2005
We have derived a set of equations to describe the thermal evolution of a neutron star which undergoes small-amplitude radial pulsations. We have taken into account, in the frame of the General Theory of Relativity, the pulsation damping due to the bulk ...
Gnedin, O. Y.   +2 more
core   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Tectonic-structural systems of Mars: Is it possible to use them to reconstruct its thermal evolution? [PDF]

open access: yesGeofísica Internacional, 2004
This work tries to establish the possible relationship among cortical stresses evidenced by faults mapped in the surface and thermal evolution on Mars.
J. F. Valdés-Galicia   +1 more
doaj  

Synergistical photo-thermal-catalysis of Zn2GeO4:xFe3+ for H2 evolution in NaBH4 hydrolysis reaction

open access: yesCatalysis Communications, 2021
Herein, we reported the systematic investigation of synergistic photo-thermal-catalysis for NaBH4 hydrolysis reaction based on zinc orthogermanate. A series of Zn2GeO4:xFe3+ (x = 0 to 0.10) catalysts were prepared via solvothermal method.
Qiaoqi Li   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Finite Element Modeling of an Aircraft Tire Rolling on a Steel Drum: Experimental Investigations and Numerical Simulations

open access: yesApplied Sciences, 2018
The aim of this study is to investigate the thermal evolution of an aircraft tire rolling at high velocities up to take off values. As this kind of experiment is difficult to realize on a real runway, experimental tests were realized on aircraft tires ...
Iulian Rosu   +2 more
doaj   +1 more source

Equation of state of strongly interacting matter: spectra for thermal particles and intensity correlation of thermal photons

open access: yes, 2010
We find that an equation of state for hot hadronic matter consisting of all baryons having $M < 2$ GeV and all mesons having $M < 1.5$ GeV, along with Hagedorn resonances in thermal and chemical equilibrium, matches rather smoothly with lattice equation ...
Chatterjee, Rupa   +2 more
core   +1 more source

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