Results 41 to 50 of about 184,702 (266)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Frontiers in Earth Science, 2022 Pore and pore network evolution of shale is critical for the evaluation the pore system in shale gas reservoirs. Thermal maturation effect acts as an indispensable role in porosity evolution.
Jin Wu +10 more
doaj +1 more source
Compactness in the thermal evolution of twin stars
Physical Review C, 2023 In this work, we study for the first time the thermal evolution of twin star pairs, i.e., stars that present the same mass but different radius and compactness. We collect available equations of state that give origin to a second branch of stable compact stars with quarks in their core.
F. Lyra +4 more
openaire +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Thermal Evolution of the Impact‐Induced Cryomagma Chamber Beneath Occator Crater on Ceres
Geophysical Research Letters, 2019 The faculae in Occator Crater on dwarf planet Ceres are an accumulation of salts that have been interpreted as cryovolcanic products. Current age estimates from crater counting suggest a maximum 18‐Ma difference between the crater forming impact and the ...
M. A. Hesse, J. C. Castillo‐Rogez
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Thermal evolution of a pulsating neutron star [PDF]
Monthly Notices of the Royal Astronomical Society, 2005 We have derived a set of equations to describe the thermal evolution of a neutron star which undergoes small-amplitude radial pulsations. We have taken into account, in the frame of the General Theory of Relativity, the pulsation damping due to the bulk and shear viscosity and the accompanying heating of the star.
Gusakov, M. E. +2 more
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tectonic-structural systems of Mars: Is it possible to use them to reconstruct its thermal evolution? [PDF]
Geofísica Internacional, 2004 This work tries to establish the possible relationship among cortical stresses evidenced by faults mapped in the surface and thermal evolution on Mars.
J. F. Valdés-Galicia +1 more
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