Results 51 to 60 of about 838,981 (293)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Effects of Y content on microstructures and thermal expansion behavior of Mg-Al-Y alloys

open access: yesMaterials Research Express, 2021
Low thermal expansion alloys play an important role in the applications of high-precision instruments because of their excellent dimensional stability under thermal shock. Hence, the effect of Y content on coefficient of thermal expansion (CTE) of Mg-1Al-
Hongbin Ma, Zhuohua Li, Jinhui Wang
doaj   +1 more source

Calculation of the Anisotropic Coefficients of Thermal Expansion: A First-Principles Approach [PDF]

open access: yes, 2019
Predictions of the anisotropic coefficients of thermal expansion are needed to not only compare to experimental measurement, but also as input for macroscopic modeling of devices which operate over a large temperature range.
Løvvik, Ole M., Pike, Nicholas A.
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

IRREVERSIBLE THERMAL EXPANSION OF REPLICATED ALUMINIUM FOAM

open access: yesActa Metallurgica Slovaca, 2018
Irreversible thermal expansion of large items made of the replicated aluminium foam was detected during the extraction of soluble filler from Al-NaCl composite. Sources of the phenomenon were investigated The expansion discovered was caused by incomplete
Arkady Finkelstein, Dmitry Husnullin
doaj   +1 more source

Thermal expansion coefficient of few-layer MoS2 studied by temperature-dependent Raman spectroscopy

open access: yesScientific Reports, 2021
The thermal expansion coefficient is an important thermal parameter that influences the performance of nanodevices based on two-dimensional materials. To obtain the thermal expansion coefficient of few-layer MoS2, suspended MoS2 and supported MoS2 were ...
Zhongtao Lin   +5 more
doaj   +1 more source

Understanding the role of guest ions in the control of thermal expansion of FeFe(CN)6

open access: yesResults in Physics, 2022
Understanding the role of guest species in framework materials is important to successfully achieve the control of thermal expansion. In this work, the thermal expansion of the Prussian blue analogue FeFe(CN)6 has been effectively tailored from negative,
Qilong Gao   +8 more
doaj   +1 more source

Porous composite with negative thermal expansion obtained by photopolymer additive manufacturing

open access: yes, 2015
Additive manufacturing (AM) could be a novel method of fabricating composite and porous materials having various effective performances based on mechanisms of their internal geometries.
Kitamura, Mitsuru   +2 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Contribution of thermal expansion and

open access: yesCondensed Matter Physics, 2007
A theoretical model is developed to describe the experimental results obtained for the isobaric thermal conductivity of rare gas solids (RGS). The isobaric thermal conductivity of RGS has been analysed within Debye approximation with regard to the effect
O.I.Pursky, V.A.Konstantinov
doaj   +1 more source

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