Results 31 to 40 of about 1,999 (196)

Constructing an entangled Unruh Otto engine and its efficiency

Journal of High Energy Physics, 2022
Uniformly accelerated frame mimics a thermal bath whose temperature is proportional to the proper acceleration. Using this phenomenon we give a detailed construction of an Otto cycle between two energy eigenstates of a system, consists of two entangled ...
Dipankar Barman, Bibhas Ranjan Majhi
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Unruh quantum Otto engine in the presence of a reflecting boundary

Journal of High Energy Physics, 2022
We introduce a new model of relativistic quantum analogue of the classical Otto engine in the presence of a perfectly reflecting boundary. A single qubit acts as the working substance interacting with a massless quantum scalar field, with the boundary ...
Arnab Mukherjee, Sunandan Gangopadhyay, A. S. Majumdar   +2 more
doaj   +1 more source

Finite size effects in thermal field theory [PDF]

Journal of Mathematical Physics, 2004
We consider a neutral self-interacting massive scalar field defined in a d-dimensional Euclidean space. Assuming thermal equilibrium, we discuss the one-loop perturbative renormalization of this theory in the presence of rigid boundary surfaces (two parallel hyperplanes), which break translational symmetry.
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Beyond the Boltzmann equation for weakly coupled quantum fields

Journal of High Energy Physics
We study the kinetic theory of a weakly interacting quantum field. Assuming a state that is close to homogeneous and stationary, we derive a closed kinetic equation for the rate of change of the occupation numbers, perturbatively in the coupling.
Xu-Yao Hu, Vladimir Rosenhaus
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

OTOC and quamtum chaos of interacting scalar fields

Journal of High Energy Physics
Discretizing the λϕ 4 scalar field theory on a lattice yields a system of coupled anharmonic oscillators with quadratic and quartic potentials. We begin by analyzing the two coupled oscillators in the second quantization method to derive several analytic
Wung-Hong Huang
doaj   +1 more source

Mean-field theory of failed thermalizing avalanches

Physical Review B, 2022
We show that localization in quasiperiodically modulated, two-dimensional systems is stable to the presence of a finite density of ergodic grains. This contrasts with the case of randomly modulated systems, where such grains seed thermalizing avalanches.
P. J. D. Crowley, A. Chandran
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source