Results 41 to 50 of about 764,055 (296)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The holographic screen at low temperatures
, 2011 A permissible spectrum of transverse vibrations for the holographic screen modifies both a distribution of thermal energy over bits at low temperatures and the law of gravitation at small accelerations of free fall in agreement with observations of flat ...
Kiselev, V. V., Timofeev, S. A.
core +1 more source
tRNA Modifications: Impact on Structure and Thermal Adaptation [PDF]
Biomolecules, 2017 Transfer RNAs (tRNAs) are central players in translation, functioning as adapter molecules between the informational level of nucleic acids and the functional level of proteins. They show a highly conserved secondary and tertiary structure and the highest density of post-transcriptional modifications among all RNAs.
Christian Lorenz +2 more
openaire +4 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Thermal conductivity of anisotropic and frustrated spin-1/2 chains [PDF]
, 2002 We analyze the thermal conductivity of anisotropic and frustrated spin-1/2 chains using analytical and numerical techniques. This includes mean-field theory based on the Jordan-Wigner transformation, bosonization, and exact diagonalization of systems ...
A. Honecker +16 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Heat exchanger tubes supported in high vibration environment [PDF]
, 1966 Cantilevered structure supports heat exchanger coils against vibration loading while allowing freedom for differential thermal growth. The support channels will accept a variety of coil angles with the same coil pitch, thus reducing the number of parts ...
Urquidi, R.
core +1 more source
, 2002 Modification of the renormalization-group approach, invoking Stratonovich transformation at each step, is proposed to describe phase transitions in 3D Ising-class systems. The proposed method is closely related to the mean-field approximation.
A. N. Rubtsov +14 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source