Results 41 to 50 of about 2,843,551 (299)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Experimental and numerical analysis of thermal performance of shape stabilized PCM in a solar thermal collector [PDF]

open access: yes, 2022
A typical solar domestic water heating system suffers from low energy efficiency due to multiple heat transfer process among components, i.e., the solar thermal collector and the thermal energy storage.
Boonk, K.J.F.   +7 more
core   +2 more sources

New Composite Materials Based on Chitosan Films Reinforced with Chitin Nanofibrils for Cosmetic Application

open access: yesCosmetics, 2023
Bioactive biodegradable chitosan films containing chitin nanofibrils have been developed for use as face masks in cosmetology. It was found that thermal modification of chitosan films promotes the transformation of the polymer into insoluble form without
Vera V. Kodolova-Chukhontseva   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Thermal Modification of Wood—A Review

open access: yesSustainable Chemistry
The thermal modification of wood has emerged as a sustainable and effective method for enhancing the physical, chemical, and mechanical properties of wood without the use of harmful chemicals. This review summarizes the current state-of-the-art in thermal wood modification, focusing on the mechanisms of wood degradation during treatment and the ...
Veronika Jančíková, Michal Jablonský
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Effect of Phosphates and Fluorides, Included in TiO2 Nanotube Layers on the Performance of Hydrogen Peroxide Detection [PDF]

open access: yesArchives of Metallurgy and Materials, 2018
Titania nanotube (TNT) arrays fabricated by anodizing of titanium foil in organic (ethylene glycol) and inorganic (phosphoric acid) electrolytes and thermally modified in argon revealed much improved properties to detect hydrogen peroxide.
K. Arkusz, E. Krasicka-Cydzik
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Modification of polyoxymethylene for increased thermal resistance [PDF]

open access: yesPolymer Engineering & Science, 2017
Ternary nanocomposites, composed of polyoxymethylene (POM), ethylene octene copolymer and zinc oxide (ZnO), are prepared by melt compounding. The effects of two types of ethylene‐octene copolymers, differing with α‐octene content (38% for EOC38 and 17% for EOC17), as well as nanostructured ZnO on thermal behavior of POM are investigated. The content of
Remo Merijs Meri   +5 more
openaire   +3 more sources

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