Results 61 to 70 of about 2,843,551 (299)

Ultrasound Modification

open access: yes, 2022
Tremendous physicochemical and techno-functional activity of gums make them a good candidate to be widely applied in various fields including food, nutra/pharmaceutical, medical, cosmetics, and biosensors.
Subasi, Büsra Gültekin   +3 more
core   +1 more source

Effects of thermal modification on the water resistance and colour stability of wood species from Bosnia and Herzegovina

open access: yesLes
This study investigates the impact of thermal modification on the water resistance and colour stability of Indigenous wood species from Bosnia and Herzegovina, including Norway spruce (Picea abies), silver fir (Abies alba), oak (Quercus sp.), and walnut
Redžo Hasanagić   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Thermal modification processes, properties, and environmental impacts [PDF]

open access: yes, 2020
This paper explores the different ways wood is thermally treated in particular looking at thermal treatment processes, properties produced, environmental impacts and market opportunities. Review is done on different processes that are currently on the
Kumer, Evan J.
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

INFLUENCE OF THERMAL TREATMENT OF THE BASALT TUFA ON ITS PHASE COMPOSITION AND SORPTION CAPACITY

open access: yesFood and Environment Safety, 2018
The results reflecting influence of thermal treatment of basalt tufa (BT) on its phase composition and capacity of some heavy metal ions (Cu2+, Mn2+, Ni2+, Pb2+, Zn2+) sorption under the static conditions are presented.
Volodymyr DIICHUK   +2 more
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Dimensional Stability and Equilibrium Moisture Content of Thermally Modified Hardwoods

open access: yesBioResources
The dimensional stability and equilibrium moisture content (EMC) of thermally modified hardwoods were studied. Lumber of yellow-poplar (Liriodendron tulipifera); red oak (Quercus borealis); white ash (Fraxinus americana), red maple (Acer rubrum); hickory
Abasali Masoumi, Brian Bond
doaj   +2 more sources

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